Cyclic hypersomnolence with symptoms of narcolepsy with cataplexy: An unusual presentation of probable immune-mediated encephalitis.

eNeurologicalSci

Department of Neurosciences, University of California, San Diego 9500 Gilman Drive #0935, La Jolla, CA 92093, USA.

Published: March 2018

We report a case of probable encephalitis presenting as narcolepsy with cataplexy, but with cyclical exacerbation and cognitive difficulties. Our patient continued to worsen despite treatment for narcolepsy and later was thought to have an immune-mediated encephalopathy. Treatment with intravenous gamma immunoglobulin (IVIG) led to complete recovery. Cyclic symptoms of narcolepsy with cataplexy are thus one presentation of probable immune-mediated encephalitis.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5933995PMC
http://dx.doi.org/10.1016/j.ensci.2018.01.003DOI Listing

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