AI Article Synopsis
- Adult pharyngitis is often not caused by group A streptococci, and using a rapid antigen test (RADT) can lead to better antibiotic prescribing practices.
- Two clinics tested the effectiveness of RADTs alongside a Group A DNA probe test (GADNA), with one clinic performing tests and the other serving as a control.
- Results showed that the clinic using RADTs had significantly lower rates of inappropriate antibiotic prescriptions compared to the control clinic, indicating that RADTs can help reduce unnecessary antibiotic use.
Article Abstract
Introduction: Adult pharyngitis is rarely attributable to group A streptococci. Utilization of a rapid streptococcal antigen test (RADT) may improve appropriate prescribing for bacterial pharyngitis.
Methods: Clinic 1 performed RADTs with subsequent Group A DNA probe test (GADNA) from November 2014-March 2015 and November 2015-March 2016 while Clinic 2 was the control clinic, then implemented the RADT with a GADNA from November 2015-March 2016. All GADNA results were obtained for each clinic from October 2013-March 2016.
Results: At Clinic 1, 22.2% versus 8.5% of patients received inappropriately prescribed antibiotics for a GADNA or RADT result, respectively (p=0.048). For Clinic 2, 51.1% compared to 21.4% of patients were inappropriately prescribed antibiotic for a GADNA or RADT result, respectively (p=0.038). Overall, the total GADNA without RADT testing or RADTs with subsequent GADNA testing, 41.6% versus 11% of patients were inappropriately prescribed antibiotics, respectively (p=<0.0001).
Conclusion: Utilizing the RADT prevented unnecessary prescribing of antibiotics in adults.
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| http://dx.doi.org/10.1016/j.diagmicrobio.2018.03.018 | DOI Listing |
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