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Atypical localization of metastatic melanoma in the gastrointestinal tract.
Rev Esp Enferm Dig
September 2024
Medicina Interna, Hospital Universitario de Getafe, España.
Although most melanomas are diagnosed in early stages of the disease, a significant percentage show metastases from the beginning or during follow-up. The most common route is lymphatic, while hematogenous spread is less frequent. The most common site for metastases is the skin itself, although they can also occur in other organs, including the digestive tract, where the small intestine is the most frequently affected organ (2).
View Article and Find Full Text PDFGut Dysbiosis Drives Inflammatory Bowel Disease Through the CCL4L2-VSIR Axis in Glycogen Storage Disease.
Adv Sci (Weinh)
August 2024
Department of Pediatrics, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, China.
Article Synopsis
- * This study identifies distinct digestive symptoms in GSD-Ib patients, including deep ulcers and strictures, and reveals that their gut microbiota and immune responses differ from typical IBD cases.
- * The research highlights a specific pathway (CCL4L2-VSIR axis) that could be targeted for therapy, aiming to improve gut health and manage IBD in GSD-Ib patients.
[Clinicopathological and molecular genetic features of Crohn's disease].
Zhonghua Bing Li Xue Za Zhi
April 2024
Department of Pathology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
To investigate the clinicopathological and molecular genetic characteristics of Crohn's disease (CD). A retrospective analysis was conducted on 52 CD patients who underwent surgical resection at the First Affiliated Hospital of Nanjing Medical University between January 2014 and June 2023. Clinical presentations and histopathological features were assessed.
View Article and Find Full Text PDFClinical features of inflammatory bowel disease unclassified: a case-control study.
BMC Gastroenterol
March 2024
Department of Gastroenterology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, No.1 Shuai Fu Yuan, Dong Cheng District, 100730, Beijing, China.
Background: Approximately 10-15% of inflammatory bowel disease (IBD) patients with overlapping features of ulcerative colitis (UC) and Crohn's disease (CD) are termed as inflammatory bowel disease unclassified (IBDU). This study aimed to describe the clinical features of IBDU and evaluate the potential associated factors of reclassification.
Methods: The clinical data of 37 IBDU patients were retrospectively analyzed from November 2012 to November 2020.
Sonographic detection of massive colonic pseudopolyposis in inflammatory bowel diseases.
J Ultrasound
March 2024
Gastroenterology Unit, Luigi Sacco University Hospital, University of Milan, Milan, Italy.
Purpose: Colonic pseudopolyps are a frequent finding in inflammatory bowel disease (IBD). Yet there are no published data describing the characteristics of pseudopolyposis in intestinal ultrasound (IUS). This study aimed at identifying the key features of pseudopolyposis in IUS.
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