In this paper we'll shed some light on well-known physical parameters to introduce them as new tools, biophysical markers, for diagnosis and prognosis of the molecular, cellular, tissue and organ biosystems such as Haemoglobin representing the macromolecules' category. Where the data reveal a lot of information about the effect of radiation dose rate on the macromolecule that are not discovered by conventional ways. Also, data put forward the dielectric and thermodynamical parameters and classify them as premiers and superiors for the detection of any disturbance that occurs in the electrical homogeneity of the macromolecule. The interesting results showed an inverse response of the Hb molecule toward higher and lower dose rates for all tested parameters, Static permittivity and change in the following thermodynamical state functions Helmholtz free energy, internal energy and entropy.
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| http://dx.doi.org/10.1016/j.pbiomolbio.2018.04.010 | DOI Listing |
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