Ningmitai Capsule is a classical patent medicine prepared from multiple effective ingredients of Chinese herbal medicine, with a wide range of biological activities and a significant efficacy in the treatment of urogenital diseases. Ningmitai Capsule has been widely applied in the management of urological and andrological diseases, with a particularly ideal effect on chronic prostatitis, since its first introduction nearly 20 years ago. With no obvious adverse effect on the male reproductive system, it has also been gaining a gradual application in the treatment of such diseases as urinary tract infections, diabetes, non-gonococcal urethritis, seminal vesiculitis, acute epididymitis, overactive bladder, hematuria, and semen non-liquefaction. However, the definite efficacy of Ningmitai Capsule needs to be further verified with more large-scale multi-centered randomized controlled trials, and its pharmacological mechanism remains to be further explored via more biomolecular experiments. The present article focuses on the recent advances in the application and studies of Ningmitai Capsule in the treatment of urological and andrological diseases.
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Ningmitai capsules have anti-inflammatory and pain-relieving effects in the chronic prostatitis/chronic pelvic pain syndrome mouse model through systemic immunity.
Front Pharmacol
October 2022
Reproductive Medicine Research Center, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) seriously affects the physical and mental health of approximately 90% of males. Due to its complex and unclear etiology, the treatment methods that are currently available for chronic prostatitis/chronic pelvic pain syndrome are controversial, and their efficacy is unsatisfactory. At present, most researchers believe that this kind of prostatitis is caused by autoimmune inflammation.
View Article and Find Full Text PDF[Systematic review and Meta-analysis of efficacy and safety of Ningmitai Capsules in treatment of urinary tract infection].
Zhongguo Zhong Yao Za Zhi
July 2022
Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences Beijing 100700, China.
Article Synopsis
- This study assesses the effectiveness and safety of Ningmitai Capsules for treating urinary tract infections (UTIs) by reviewing randomized controlled trials from multiple medical databases.
- The meta-analysis included 17 studies with nearly 2,000 participants, revealing that Ningmitai Capsules combined with standard antibiotics led to better outcomes, such as higher clinical cure rates and quicker symptom relief.
- The results indicated significant improvements for treating acute pyelonephritis and diabetes-related UTIs, outperforming conventional antibiotics alone in various measurable outcomes.
Ningmitai capsule promotes calculi expulsion after RIRS for 10-20-mm upper urinary stones: a multicenter, prospective, randomized controlled trial.
Urolithiasis
April 2022
Department of Urology, The Second Affiliated Hospital of Zhengzhou University, No. 2 Jingba Road, Zhengzhou, 450014, Henan, China.
To evaluate the efficacy and safety of the use of Ningmitai capsule as an adjunctive stone expulsion therapy after RIRS. All patients were diagnosed with upper urinary tract calculi measuring 10-20 mm. The patients who successfully underwent RIRS were randomly assigned to the NMT capsule group (Ningmitai capsule, 1.
View Article and Find Full Text PDF[Herb-separated moxibustion on navel combined with capsule for non-liquefaction semen with dampness and heat diffusing downward: a randomized controlled trial].
Zhongguo Zhen Jiu
December 2021
College of Acupuncture-Moxibustion and Tuina, Shandong University of TCM, Jinan 250355, China.
Objective: To compare the clinical therapeutic effect between herb-separated moxibustion on navel combined with capsule and simple capsule for non-liquefaction semen with dampness and heat diffusing downward.
Methods: A total of 66 patients with non-liquefaction semen of dampness and heat diffusing downward were randomized into an observation group (33 cases, 2 cases dropped off) and a control group (33 cases, 2 cases dropped off). In the control group, capsule was given orally 3 times a day.
[Efficacy and adverse effects of Ningmitai Capsules combined with antibiotics in the treatment of chronic prostatitis: A meta-analysis].
Zhonghua Nan Ke Xue
March 2021
Key Laboratory of the Ministry of Education for Public Health Security / Key Laboratory of the National Health Commission for Assessment of Health Technology / Research Center of Clinical Epidemiology, Fudan University School of Public Health, Shanghai 200032, China.
Objective: To study the effect, treatment course and adverse reactions of Ningmitai Capsules (NMT) in the treatment of chronic prostatitis (CP).
Methods: We searched the CNKI, Wanfang, COMDD and VIP databases, Cochrane Library, PubMed, EMBASE and Chinese academic conference papers for related articles before October 2019 on the treatment of CP with NMT, evaluated the quality of the literature with the Jadad Scale, and conducted a meta-analysis using the Stata14 software.
Results: Totally, 20 articles were included in this study, involving 3558 cases of CP, 1807 in the observation group and 1751 as controls.
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