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Folic acid and methotrexate use and their association with COVID-19 diagnosis and mortality: a case-control analysis from the UK Biobank.
BMJ Open
August 2022
Division of Clinical Immunology and Rheumatology, The University of Alabama at Birmingham, Birmingham, Alabama, USA
Objective: To determine if methotrexate or folic acid prescription was associated with differential risk for COVID-19 diagnosis or mortality.
Design: Case-control analysis.
Setting: The population-based UK Biobank (UKBB) cohort.
Gout and the risk of COVID-19 diagnosis and death in the UK Biobank: a population-based study.
Lancet Rheumatol
April 2022
Biochemistry Department, University of Otago, Dunedin, New Zealand.
Background: There is a paucity of data on outcomes for people with gout and COVID-19. We aimed to assess whether gout is a risk factor for diagnosis of COVID-19 and COVID-19-related death, and to test for sex- and drug-specific differences in risk.
Methods: We used data from the UK Biobank, which included 15 871 people with gout.
Gout, Rheumatoid Arthritis, and the Risk of Death Related to Coronavirus Disease 2019: An Analysis of the UK Biobank.
ACR Open Rheumatol
May 2021
University of Otago, Dunedin, New Zealand, and University of Alabama at Birmingham.
Objectives: The objectives for this study were to assess whether gout and/or rheumatoid arthritis (RA) are risk factors for coronavirus disease 2019 (COVID-19) diagnosis and to assess whether gout and/or RA are risk factors for death from COVID-19.
Methods: We used data from the UK Biobank. Multivariable-adjusted logistic regression was employed in the following analyses: analysis A, to test for association between gout and/or RA and COVID-19 diagnosis (n = 473,139); analysis B, to test for association between gout and/or RA and death from COVID-19 in a case-control cohort of people who died of or survived COVID-19 (n = 2059); analysis C, to test for association between gout and/or RA and death from COVID-19 in the entire UK Biobank cohort (n = 473,139).
Common variants of EDA are associated with non-syndromic hypodontia.
Orthod Craniofac Res
February 2021
Faculty of Dentistry, Sir John Walsh Research Institute, University of Otago, Dunedin, New Zealand.
Objective: The aim of this case-control study was to investigate the association between non-syndromic hypodontia and nineteen common variants of candidate genes ectodysplasin A (EDA), paired box 9 (PAX9), msh homeobox 1 (MSX1) and axis inhibition protein 2 (AXIN2).
Settings And Sample Population: Sixty-one hypodontia cases were frequency-matched to 253 controls with no missing teeth (excluding the third molars).
Material And Methods: Self-report data and DNA samples were collected from each participant.
The Novel Eryngii Method of Nipple Reduction for Female-to-Male Transsexuals.
Acta Med Okayama
February 2020
Department of Gender Center, Okayama University Hospital, Okayama 700-8558, Japan.
Mastectomy is usually the first and most important surgical procedure in female-to-male (FTM) individuals with gender identity disorder. Nipple reduction is also important in the process of reconstructing the chest wall for a more male appearance. If the nipples remain large after a mastectomy, the results may be disappointing to many FTM transsexuals.
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