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A CT-Based Lung Radiomics Nomogram for Classifying the Severity of Chronic Obstructive Pulmonary Disease.
Int J Chron Obstruct Pulmon Dis
December 2024
Department of Radiology, Second Affiliated Hospital of Naval Medical University, Shanghai, People's Republic of China.
Background: Chronic obstructive pulmonary disease (COPD) is a major global health concern, and while traditional pulmonary function tests are effective, recent radiomics advancements offer enhanced evaluation by providing detailed insights into the heterogeneous lung changes.
Purpose: To develop and validate a radiomics nomogram based on clinical and whole-lung computed tomography (CT) radiomics features to stratify COPD severity.
Patients And Methods: One thousand ninety-nine patients with COPD (including 308, 132, and 659 in the training, internal and external validation sets, respectively), confirmed by pulmonary function test, were enrolled from two institutions.
The Pivotal Role of Baseline LDCT for Lung Cancer Screening in the Era of Artificial Intelligence.
Arch Bronconeumol
November 2024
Department of Experimental and Clinical Biomedical Sciences "Mario Serio", University of Florence, 50139 Florence, Italy. Electronic address:
In this narrative review, we address the ongoing challenges of lung cancer (LC) screening using chest low-dose computerized tomography (LDCT) and explore the contributions of artificial intelligence (AI), in overcoming them. We focus on evaluating the initial (baseline) LDCT examination, which provides a wealth of information relevant to the screening participant's health. This includes the detection of large-size prevalent LC and small-size malignant nodules that are typically diagnosed as LCs upon growth in subsequent annual LDCT scans.
View Article and Find Full Text PDFAccuracy, Reproducibility, and Responsiveness to Treatment of Home Spirometry in Cystic Fibrosis: Multicenter, Retrospective, Observational Study.
J Med Internet Res
December 2024
Department of Pediatric Pulmonology, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.
Article Synopsis
- Portable spirometers are becoming popular for measuring lung function at home, but there are concerns about their accuracy, which impacts the management of chronic respiratory diseases.
- The study aimed to evaluate the accuracy, repeatability, and responsiveness of home spirometry for cystic fibrosis patients in both children and adults across multiple Dutch centers.
- Results indicated that home spirometry measurements consistently showed lower values than clinic measurements, suggesting potential limitations in using these devices for accurate lung function assessment.
Development and Validation of a Novel Tool to Measure Medication Adherence for Noncommunicable Diseases in India: Protocol for an Exploratory Sequential Mixed Methods Multicentric Study.
JMIR Res Protoc
December 2024
Achutha Menon Centre for Health Science Studies, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.
Background: In high-income countries, only 50% of patients treated for chronic diseases adhere to the prescribed treatment. This issue is even more pronounced in resource-limited countries. Medication adherence scales are simple, low-cost approaches to identify nonadherence in clinical practice.
View Article and Find Full Text PDFA quantitative method for assessing treatment-related changes within the airway mucosa in patients with chronic bronchitis.
Respir Med
November 2024
Department of Thoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, 3500 North Broad Street, Philadelphia, PA, 19140, USA. Electronic address:
Background: No standardized method has yet been established for evaluating airway mucosal aberrancies associated with chronic obstructive pulmonary disease (COPD) or chronic bronchitis (CB). While goblet cell hyperplasia (GCH) is an established pathognomonic hallmark of the CB disease process, no standardized method exists for acquiring mucosal biopsies and assessing morphologic airway mucosa alterations. Additionally, the impacts from interventions targeting the airway mucosa are not well defined.
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