Impact of MCT1 Haploinsufficiency on the Mouse Retina.

Adv Exp Med Biol

Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.

Published: May 2019

The monocarboxylate transporter 1 (MCT1) is highly expressed in the outer retina, suggesting that it plays a critical role in photoreceptors. We examined MCT1 heterozygotes, which express half of the normal complement of MCT1. The MCT1 retina developed normally and retained normal function, indicating that MCT1 is expressed at sufficient levels to support outer retinal metabolism.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6708593PMC
http://dx.doi.org/10.1007/978-3-319-75402-4_46DOI Listing

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