Enzymatically promoted release of organic molecules linked to magnetic nanoparticles.

Beilstein J Nanotechnol

Department of Chemistry and Industrial Chemistry, Università di Genova, via Dodecaneso, 31 16146 Genova, Italy.

Published: March 2018

Magnetite-based magnetic nanoparticles have been successfully coupled to an organic system constituted of a fluorescent molecule, a tripeptide specifier and a spacer. The system is able to selectively release the fluorescent molecule upon targeted enzymatic hydrolysis promoted by a lysine/arginine specific protease.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905276PMC
http://dx.doi.org/10.3762/bjnano.9.92DOI Listing

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