A liquid crystal (LC) lens array with high light control power and a large aperture using a composited alignment layer is proposed. In our design, the alignment layer is not only used for getting a uniform arrangement of LC molecule, but also for getting a lens-like refractive index distribution in the LC layer when a voltage is applied. Through simple technology processes, a tunable focal length LC lens array with a millimeter scale diameter can be achieved. Furthermore, the maximum phase difference of the proposed LC lens array can achieve 105.38π. So, the proposed LC lens array has a high light control power.
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http://dx.doi.org/10.1364/OE.26.009254 | DOI Listing |
Biomark Res
January 2025
Department of Pancreatic Surgery, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
The tumor microenvironment functions as a dynamic and intricate ecosystem, comprising a diverse array of cellular and non-cellular components that precisely orchestrate pivotal tumor behaviors, including invasion, metastasis, and drug resistance. While unraveling the intricate interplay between the tumor microenvironment and tumor behaviors represents a tremendous challenge, recent research illuminates a crucial biological phenomenon known as cellular mechanotransduction. Within the microenvironment, mechanical cues like tensile stress, shear stress, and stiffness play a pivotal role by activating mechanosensitive effectors such as PIEZO proteins, integrins, and Yes-associated protein.
View Article and Find Full Text PDFAdv Exp Med Biol
January 2025
Department of Optometry, University of Benin, Benin City, Nigeria.
Contact lenses have become integral tools in the realm of ocular therapeutics, extending beyond their primary function of refractive correction to encompass a diverse array of therapeutic applications. This review explores the evolving role of contact lenses in managing various ocular conditions, highlighting their efficacy in enhancing patient outcomes. Initially developed to correct refractive errors, contact lenses now serve as effective vehicles for delivering medications directly to the ocular surface, offering targeted treatment for conditions such as dry eye syndrome and corneal ulcers.
View Article and Find Full Text PDFLight Sci Appl
January 2025
Institute of Modern Optics, Nankai University, Tianjin Key Laboratory of Micro-scale Optical Information Science and Technology, Tianjin, 300350, China.
A stacked metamaterial MEMS (meta-MEMS) chip is proposed, which can perfectly absorb electromagnetic waves, convert them into mechanical energy, drive movement of the optical micro-reflectors array, and detect millimeter waves. It is equivalent to using visible light to image a millimeter wave. The meta-MEMS adopts the design of upper and lower chip separation and then stacking to achieve the "dielectric-resonant-air-ground" structure, reduce the thickness of the metamaterial and MEMS structures, and improve the performance of millimeter wave imaging.
View Article and Find Full Text PDFBMJ Open
January 2025
Research & Innovation Institute, Women's College Hospital, Toronto, Ontario, Canada.
Introduction: Intimate partner violence (IPV) and sexual assault are pervasive public health and human rights concerns that disproportionately impact trans and gender-diverse (TGD) individuals. Experiences of cisgenderism and transphobia, compounded by racism and other forms of discrimination and structural violence, can hinder access to appropriate supports in a safe and non-stigmatising environment across a variety of sectors, including but not limited to healthcare, social services, criminal justice, and legal. TGD individuals may also have unique health and social needs requiring support that is not yet in place.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Dalian University of Technology State Key Laboratory of High-Performance Precision Manufacturing, Key Laboratory for Micro/Nano Technology and System of Liaoning Province, School of Mechanical Engineering, Dalian 116024, China.
Inspired by ancient trilobites, novel curved microlens arrays (CMLAs) were designed. Direct, fast, and low-cost CMLAs with two focal planes were fabricated using ultraprecision machining technology and hot embossing technology. We designed four pairs of artificial compound eyes (ACEs) composed of large and small lenses with four different curvatures to achieve focusing and imaging on two focal planes.
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