Departing from traditional server-centric data center architectures towards disaggregated systems that can offer increased resource utilization at reduced cost and energy envelopes, the use of high-port switching with highly stringent latency and bandwidth requirements becomes a necessity. We present an optical switch architecture exploiting a hybrid broadcast-and-select/wavelength routing scheme with small-scale optical feedforward buffering. The architecture is experimentally demonstrated at 10Gb/s, reporting error-free performance with a power penalty of <2.5dB. Moreover, network simulations for a 256-node system, revealed low-latency values of only 605nsec, at throughput values reaching 80% when employing 2-packet-size optical buffers, while multi-rack network performance was also investigated.
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http://dx.doi.org/10.1364/OE.26.008756 | DOI Listing |
Eye (Lond)
January 2025
Maidstone Hospital Eye Department, Hermitage Lane, Maidstone, UK.
Background And Objectives: Faricimab, a bispecific antibody targeting VEGF-A and angiopoietin-2, has shown promise in treating neovascular age-related macular degeneration (nAMD). This study evaluates 1-year outcomes of faricimab in treatment-experienced nAMD patients.
Methods: This single-centre retrospective cohort study included patients previously treated for nAMD who switched to faricimab between November 2022 and March 2024.
Biosens Bioelectron
January 2025
Key Laboratory of Laboratory Medical Diagnostics, Ministry of Education, Department of Laboratory Medicine, Chongqing Medical University, Chongqing, China. Electronic address:
Isothermal amplification-based nucleic acid detection technologies have become rapid and efficient tools for molecular diagnostics. Sequence-specific monitoring methods are crucial for isothermal amplification, as they help identify the occurrence of extended primer dimers, which can lead to false positive results. Fluorescent aptamers are promising tools for real-time monitoring of isothermal amplification but are inherently limited by thermostability.
View Article and Find Full Text PDFNat Commun
January 2025
Key Laboratory of Polar Materials and Devices (Ministry of Education), Shanghai Center of Brain-Inspired Intelligent Materials and Devices, Department of Electronics, East China Normal University, Shanghai, 200241, China.
Moiré superlattices in two-dimensional stacks have attracted worldwide interest due to their unique electronic properties. A typical example is the moiré ferroelectricity, where adjacent moirés exhibit opposite spontaneous polarization that can be switched through interlayer sliding. However, in contrast to ideal regular ferroelectric moiré domains (equilateral triangles) built in most theoretical models, the unavoidable irregular moiré supercells (non-equilateral triangles) induced by external strain fields during the transfer process have been given less attention.
View Article and Find Full Text PDFExp Eye Res
January 2025
Department of Ophthalmology & Visual Science, Eye & ENT Hospital, Shanghai Medical College, Fudan University, Shanghai 200031, China; NHC Key Laboratory of Myopia, Chinese Academy of Medical Sciences, and Shanghai Key Laboratory of Visual Impairment and Restoration (Fudan University), Shanghai 200031, China. Electronic address:
The periocular mesenchyme (POM) gives rise to key structures in the ocular anterior segment, and its malformation leads to anterior segment dysgenesis (ASD) with iridocorneal angle (ICA) abnormalities. However, the transcriptional profile of the POM and the regulatory mechanisms governing cell-fate decision during anterior eye and ICA development remain poorly understood. In this study, we performed a comprehensive time-series analysis by sequencing rat anterior ocular samples collected at five consecutive perinatal stages: embryonic days 16.
View Article and Find Full Text PDFInorg Chem
January 2025
Department of Chemistry, College of Sciences, Northeastern University, Shenyang, Liaoning 110819, China.
Copper-based halides have attracted significant attention due to their unique photophysical properties and diverse coordination configurations. However, enhancing water stability and modulating structural transitions in cuprous halide materials remain challenging. In this work, we successfully synthesized three copper(I) halides, (CHP)CuBr (L1, [CHP] = hexyltriphenylphosphonium), (CHP)CuBr (L2), and (CHP)CuI (L3), via solvent volatilization, demonstrating exceptional water stability even after 27 days of submersion.
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