AI Article Synopsis
- The research showcases the creation of three new polycyclic structures featuring sulfoximines, highlighting their potential in drug discovery.
- The designs incorporate multiple points for modification and exhibit significant sp-character, making them intriguing 3D frameworks.
- The synthesized compounds are now included in the European Lead Factory's compound collection for further exploration.
Article Abstract
The design and synthesis of three novel polycyclic scaffolds containing sulfoximines are presented in this work, which exemplify that sulfoximines represent a real opportunity for the discovery of new drug candidates. Additionally, the structures present at least two points of diversification and contain a high level of sp-character, hence being very interesting 3D scaffolds. The compounds synthesized were added to the compound collection of the European Lead Factory.
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Article Synopsis
- The research showcases the creation of three new polycyclic structures featuring sulfoximines, highlighting their potential in drug discovery.
- The designs incorporate multiple points for modification and exhibit significant sp-character, making them intriguing 3D frameworks.
- The synthesized compounds are now included in the European Lead Factory's compound collection for further exploration.
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