Gold Glyconanoparticles as Water-Soluble Polyvalent Models To Study Carbohydrate Interactions.

Angew Chem Int Ed Engl

Grupo de Carbohidratos Instituto de Investigaciones Químicas, CSIC Isla de la Cartuja, Américo Vespucio s/n, 41092 Sevilla (Spain) Fax: (+34) 95-448-95-63.

Published: June 2001

Glycosphingolipid clustering and interactions at the cell membrane can be modeled by gold glyconanoparticles prepared with biologically significant oligosaccharides. Such water-soluble gold glyconanoparticles with highly polyvalent carbohydrate displays (see picture, gray hemisphere: gold nanoparticle) have been obtained by a simple and versatile strategy.

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http://dx.doi.org/10.1002/1521-3773(20010618)40:12<2257::AID-ANIE2257>3.0.CO;2-SDOI Listing

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