Osteoblasts: yes, platelets: no! Bone implants have to be integrated with the surrounding tissue to allow a smooth and stable connection. A new procedure is shown which is based on covalent linking of a highly selective RGD peptide to a poly(methyl methacrylate) (PMMA) material (see picture). Osteoblasts very effectively bind to the treated surface and are stimulated to proliferate.
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| http://dx.doi.org/10.1002/(SICI)1521-3773(19990215)38:4<560::AID-ANIE560>3.0.CO;2-F | DOI Listing |
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