Total Synthesis of the CP Molecules CP-263,114 and CP-225,917- Part 1: Synthesis of Key Intermediates and Intelligence Gathering.

Angew Chem Int Ed Engl

Department of Chemistry, and The Skaggs Institute for Chemical Biology, The Scripps Research Institute, 10550 North Torrey Pines Road, La Jolla, California 92037 (USA), Fax: (+1) 619-784-2469 (and) Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093 (USA).

Published: June 1999

Download full-text PDF

Source
http://dx.doi.org/10.1002/(SICI)1521-3773(19990601)38:11<1669::AID-ANIE1669>3.0.CO;2-DDOI Listing

Publication Analysis

Top Keywords

total synthesis
4
synthesis molecules
4
molecules cp-263114
4
cp-263114 cp-225917-
4
cp-225917- synthesis
4
synthesis key
4
key intermediates
4
intermediates intelligence
4
intelligence gathering
4
total
1

Similar Publications

Benzo (a) pyrene produced by food during high-temperature process enters the body through ingestion, which causes food safety issues to the human body. In order to alleviate the harm of foodborne benzo (a) pyrene to human health, a strain that can degrade benzo (a) pyrene was screened from Kefir, a traditional fermented product in Xinjiang. Bacillus cereus M72-4 is a Gram-positive bacteria sourced from Xinjiang traditional fermented product Kefir, under Benzo(a)pyrene stress conditions, there was 69.

View Article and Find Full Text PDF

Oxidative damage, oxidative inflammation, and a range of downstream diseases represent significant threats to human health. The application of natural antioxidants and anti-inflammatory agents can help prevent and mitigate these associated diseases. In this study, we aimed to investigate the effectiveness of walnut green husk (WNGH) as an antioxidant and anti-inflammatory agent in an in vitro setting.

View Article and Find Full Text PDF

Introduction: Lupus nephritis (LN) is one of the most frequent and serious organic manifestations of systemic lupus erythematosus (SLE). Autophagy, a new form of programmed cell death, has been implicated in a variety of renal diseases, but the relationship between autophagy and LN remains unelucidated.

Methods: We analyzed differentially expressed genes (DEGs) in kidney tissues from 14 LN patients and 7 normal controls using the GSE112943 dataset.

View Article and Find Full Text PDF

: The synthesis of fluoridated apatite consists of several stages, among which the heat treatment has a significant impact on the physical and chemical properties. The present study aims to elucidate the influence of two different sintering methods on fluoride-substituted apatite properties. : For this purpose, a two F-substituted apatites were produced by heat treatment in different ways called "rapid sintering" and "slow sintering".

View Article and Find Full Text PDF

Correlation between body composition variables, plantar pressure and pain level.

Acta Bioeng Biomech

September 2024

PhD, Associate Professor and Researcher Sports Science Department, Vice-president of Faculty of Human Social Sciences University of Beira Interior, Covilhã, Portugal; Research Center in Sports, Health and Human Development, Covilhã, Portugal.

From a current perspective, it is understood that body posture is influenced by individual asymmetries, cultural context, habitual body patterns, etiological factors and psychosocial factors allocated to the individual. Clarifying the musculoskeletal cause that originated the postural alteration is considered the clinical challenge in the treatment of pain or discomfort. Recent studies have shown the influence of changes in body weight on the distribution of plantar pressure and foot pain, emphasizing the importance of understanding these relationships.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!