Organocatalyzed Synthesis of [3.2.1] Bicyclooctanes.

Molecules

Departamento de Química Orgánica, Universidad de Salamanca, Plaza de los Caídos 1⁻5, 37008 Salamanca, Spain.

Published: April 2018

Organocatalysis constitutes one of the main research areas in organic chemistry from the last two decades. This chemistry has been applied to the synthesis of many natural products and structures in a manner that reduces the residues and so the ecological impact. In this review, we consider the work that has been done for the synthesis of bicyclo[3.2.1]octane framework. This structure is present in many natural products with very important biological activities.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099548PMC
http://dx.doi.org/10.3390/molecules23051039DOI Listing

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