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Pulmonary hypertension as a prognostic marker in low-flow low-gradient aortic stenosis: Insights from invasive hemodynamics and post-TAVR outcomes.
Int J Cardiol
December 2024
Division of Adult Cardiology, National Heart Center, The Royal Hospital, Muscat, Oman; Ministry of Health, Muscat, Oman.
Introduction: Pulmonary hypertension (PH) is a common and significant comorbidity in patients with low-flow low-gradient (LF-LG) aortic stenosis, impacting prognosis after transcatheter aortic valve replacement (TAVR). Non-invasive tools often fail to capture PH's full clinical impact due to inherent limitations. This study evaluates the prognostic significance of PH measured invasively and explores its implications on post-TAVR outcomes.
View Article and Find Full Text PDF2024 Update on Cerebral Embolic Protection After Transcatheter Aortic Valve Replacement.
J Clin Med
November 2024
Collegium Medicum-Faculty of Medicine, WSB University, 41-300 Dabrowa Gornicza, Poland.
Cerebral embolic protection (CEP) during transcatheter aortic valve replacement (TAVR) has emerged as an important tool in reducing stroke risk associated with this intervention. With the recent expansion of TAVR into lower-risk populations, the role of preventive strategies gained greater significance. Despite advancements in TAVR technologies, peri-procedural stroke remains a significant complication, with rates ranging between 2 and 5%.
View Article and Find Full Text PDFParameterization, algorithmic modeling, and fluid-structure interaction analysis for generative design of transcatheter aortic valves.
Eng Comput
June 2024
Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN USA.
Heart valves play a critical role in maintaining proper cardiovascular function in the human heart; however, valve diseases can lead to improper valvular function and reduced cardiovascular performance. Depending on the extent and severity of the valvular disease, replacement operations are often required to ensure that the heart continues to operate properly in the cardiac system. Transcatheter aortic valve replacement (TAVR) procedures have recently emerged as a promising alternative to surgical replacement approaches because the percutaneous methods used in these implant operations are significantly less invasive than open heart surgery.
View Article and Find Full Text PDFThe influence of lipoprotein(a) on aortic valve calcification in patients undergoing transcatheter aortic valve replacement.
Clin Res Cardiol
December 2024
Clinic for General and Interventional Cardiology/Angiology, Herz- und Diabeteszentrum Nordrhein-Westfalen, Ruhr-Universität Bochum, Georgstraße 11, 32545, Bad Oeynhausen, Germany.
Background: Elevated levels of lipoprotein(a) (Lp[a]) have been recognized as substantial risk factors for cardiovascular disease and aortic stenosis (AS). However, the specific role of Lp(a) in promoting aortic valve calcification (AVC) and influencing mortality in elderly, multimorbid patients undergoing transcatheter aortic valve replacement (TAVR) remains unclear and warrants further investigation.
Methods: A retrospective analysis was conducted on all consecutive patients who underwent TAVR between August 2019 and June 2020 at our clinic.
Management of Aorto-Right Ventricular Fistulas After TAVR.
JACC Case Rep
November 2024
Department of Interventional and Structural Cardiology, Sidney Kimmel Medical College at Thomas Jefferson University, Deborah Heart and Lung Center, Philadelphia, Pennsylvania, USA.
This clinical case series reviews the diagnosis and management of aorto-right ventricular fistulas post-transcatheter aortic valve replacement, highlighting 3 cases. We emphasize early detection, individualized treatment strategies, and the role of multidisciplinary heart teams in achieving favorable outcomes. Comprehensive imaging and procedural planning are crucial for successful intervention and management of this rare complication.
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