Purpose Of Review: To review current concepts regarding the mechanisms of postoperative pain after photorefractive keratectomy (PRK) and review available treatment options.
Recent Findings: Many clinical studies have established the safety and efficacy of different topical and systematic therapeutic agents and techniques for the treatment of postoperative pain after PRK, especially topical nonsteroidal anti inflammatory agents and oral nonsteroidal and narcotic medications. New therapeutic agents and techniques are continuously studied, introducing new agents and comparing teh efficacy of different regimens. Postoperative pain severity varies widely between patients, and no single strategy has been proven best for acute pain management.
Summary: To date, the literature supports the use of topical agents such as nonsteroidal anti-inflammatory medications (NSAIDs) and diluted topical anesthetics in combination with oral agents such as opiates and NSAIDs for acute pain management. The use of local agents and techniques is preferred due to their less significant side effect profile. The use of systemic opiate agents is reserved for breakthrough pain.
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http://dx.doi.org/10.1097/ICU.0000000000000486 | DOI Listing |
Front Vet Sci
January 2025
Department for Clinical Diagnostics and Services, Section of Anaesthesiology, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
Introduction: This study aimed to investigate the analgesic efficacy of perioperative electroacupuncture in fifty-six healthy female dogs undergoing ovariohysterectomy as part of a catch-neuter-release project.
Materials And Methods: Ten minutes after sedation with 20 μg/kg medetomidine combined with 0.3 mg/kg butorphanol intramuscularly, the dogs were randomly allocated into two groups and received either electroacupuncture (EA, = 27) or sham acupuncture (C, = 29) treatment for 10 min (after sedation until the end of the surgery) at 6 different acupuncture points LI-4 (Large intestine 4), LIV-3 (Liver 3), ST-36 (Stomach 36), SP-6 (Spleen 6) bilateral.
Front Surg
January 2025
Department of Neurosurgery, Ward 2. Gansu Provincial Hospital, Lanzhou, Gansu, China.
Objective: Demonstrate the superiority of percutaneous balloon compression (PBC) in the treatment of primary trigeminal neuralgia (PTN) compared to trigeminal microvascular decompression (MVD).
Methods: Clinical data, including immediate, short-term, and long-term pain relief, complications, duration of the operation, and postoperative hospital stay, were retrospectively analyzed for 114 patients diagnosed with PTN who were treated with either PBC or MVD between January 2018 and December 2021.
Results: There were no statistically significant differences observed in the pain relief rates between the two surgical methods at 24 h postoperatively (MVD: 91.
Cureus
December 2024
Surgery, Imam Abdulrahman Bin Faisal University, Dammam, SAU.
Enhanced Recovery After Surgery (ERAS) protocols have significantly transformed the management of patients undergoing colorectal surgery. This comprehensive review explores the key components and benefits of ERAS in colorectal procedures, focusing on preoperative, perioperative, and postoperative strategies aimed at improving patient outcomes. These strategies include preoperative patient education, multimodal analgesia, minimally invasive surgical techniques, and early mobilization.
View Article and Find Full Text PDFJ Pain Res
January 2025
Daytime Anesthesiology Department, the Affiliated Hospital of Qingdao University, Qingdao, Shandong Province, People's Republic of China.
Purpose: This randomized, controlled trial aimed to assess the sedative effects of esketamine and sufentanil combined with propofol during EUS.
Patients And Methods: Three hundred and forty patients undergone EUS were randomly divided into two groups to receive esketamine 0.25 mg/kg combined with propofol (esketamine group) or sufentanil 0.
J Pain Res
January 2025
Department of Pain Management, Beijing Tiantan Hospital, Capital Medical University, Beijing, People's Republic of China.
Background: Scalp nerve blocks (SNB) may significantly reduce post-craniotomy pain (PCP) but only for a short period of time. Dexamethasone, as an adjuvant to local anesthetics, was reported to prolong the analgesia duration of never block; however, the addition of dexamethasone to SNB is rare. We therefore tested the hypothesis that dexamethasone as an adjuvant to bupivacaine in SNB is positive after craniotomy.
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