Gynoid lipodystrophy (GLD) is a structural, inflammatory, and biochemical disorder of the subcutaneous tissue causing alterations in the topography of the skin. Commonly known as "cellulite," GLD affects up to 90% of women, practically in all stages of the life cycle, beginning in puberty. It is a clinical condition that considerably affects the patients' quality of life. It is a frequent reason for consultation, although the patients resort to empirical, improvised, nonevidence-based treatments which discourage and can be a source of frustration not only because of the lack of results but also due to the complications derived from those treatments. In this article, a panel of experts from different specialties involved in the management of this clinical skin disorder presents the results of a systematic literature search and of the consensus discussion of the evidence obtained from different treatments currently available. The analysis was divided into topical, systemic, noninvasive, and minimally invasive treatments.
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Case Report: Concurrent pathogenic variants in the gene as a cause of sporadic partial lipodystrophy.
Front Genet
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Introduction: Inherited lipodystrophies are a group of rare diseases defined by severe reduction in adipose tissue mass and classified as generalized or partial. We report a non-familial (sporadic) case of partial lipodystrophy caused by a novel genetic mechanism involving closely linked pathogenic variants in the gene.
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A Retrospective Pragmatic Longitudinal Case-Series Clinical Study to Evaluate the Clinical Outcome of Triple-Frequency Ultrasound in Treatment of Cellulite.
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Wellcomet GmbH, Bruchsal, Germany.
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Methods: Twenty Caucasian females with mild-to-severe gynoid lipodystrophy aged 27-53 years who received cellulite monotherapy with TF-LDM were included in this study. All participants were evaluated at three time points: baseline (T1), on the day of the last treatment (T2), and during the last follow-up (T3).
Gynoid lipodystrophy, also called cellulite, is defined as a metabolic disorder of the subcutaneous tissue that alters body contour. It is rare in men but affects 80%-90% of adult women.The authors describe a technique for the treatment of cellulite with non-traumatic subcision of septa by cannula associated with large-gel-particle hyaluronic acid (HA).
View Article and Find Full Text PDFInfrared thermography as valuable tool for gynoid lipodystrophy (cellulite) diagnosis.
Lasers Med Sci
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Programa de Pós-Graduação Em Engenharia Biomédica, Instituto de Pesquisa & Desenvolvimento, Universidade Do Vale Do Paraíba - UNIVAP. Av. Shishima Hifumi 2911 - 12244-000, São José dos Campos, SP, Brazil.
Cellulite is a morphological alteration of the tegument tissue, directly interfering in self-esteem with etiology and pathophysiology far from being a consensus. Although the visual diagnosis of cellulitis is well known, it does not represent the real pathological condition of the subcutaneous tissue. The aim of the study was to investigate the hypothesis that the more heterogeneous tissue pattern analyzed by infrared thermography, the more severe is the cellulite grade.
View Article and Find Full Text PDFEffect of combined compression-vibration therapy using non-invasive Beautylizer Therapy Cosmospheres V on the subcutaneous tissue morphology in women with gynoid lipodystrophy (pilot study).
J Cosmet Dermatol
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Federal State Budget-Funded Educational Institution of Higher Education "Izhevsk State Medical Academy" of the Ministry of Health of Russia (FGBOU VO IGMA of the MoH of Russia), Izhevsk, Russia.
Background: Gynoid lipodystrophy is one of the most common cosmetical problems in women.
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Methods: The study enrolled 25 virtually healthy women aged 25-45 years with gynoid lipodystrophy grades I and II.
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