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Eosinophilic cellulitis, also known as Wells syndrome, presents a wide range of morphological spectrum, from pruritic erythematous papules, nodules, and pustules to urticarial and bullous lesions. This is a rare dermatological condition and is known to develop after treatment of hematological malignancy. Here, we report a case of Wells syndrome that was the initial presentation of lymphoma, preceding all other symptoms by six months.

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  • Primary atopic disorders (PAD) are rare genetic conditions caused by specific gene variants that affect skin and immune function, making diagnosis challenging among common allergic disease cases.
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  • * A 41-year-old Turkish woman experienced pruritus and tenderness in her chest, having previously been treated for recurrent abscesses and diagnosed with HES involving multiple organs.
  • * Biopsy results indicated eosinophilic infiltration in her rash, and her ongoing respiratory symptoms and childhood asthma hinted at EGPA, highlighting the importance of recognizing these conditions during Wells syndrome investigation.
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