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| http://dx.doi.org/10.1016/j.anai.2018.04.022 | DOI Listing |
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Alzheimers Dement
December 2024
Vanderbilt University Medical Center, Nashville, TN, USA.
Background: We report the case of a 79-year-old woman with Alzheimer's disease who enrolled in a clinical study of lecanemab. After the third, biweekly infusion she suffered a seizure followed by aphasia and progressive encephalopathy. Magnetic resonance imaging revealed multifocal cerebral edema and an increased burden of cerebral microhemorrhages compared to pre-trial imaging.
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Department of Pharmaceutics, Y. B. Chavan College of Pharmacy, Aurangabad, India.
Pharmaceutical giants (e.g., Ashland, Bausch & Lomb, Johnson & Johnson, Medtronic, Neurelis, etc.
View Article and Find Full Text PDF3D-Printed PCL-Based Scaffolds with High Nanosized Synthetic Smectic Clay Content: Fabrication, Mechanical Properties, and Biological Evaluation for Bone Tissue Engineering.
Int J Nanomedicine
January 2025
Interdisciplinary Laboratory for Advanced Materials (LIMAV), Materials Science and Engineering Graduate Program (PPGCM), Federal University of Piauí (UFPI), Teresina, PI, Brazil.
Background: The 3D printing of macro- and mesoporous biomimetic grafts composed of polycaprolactone (PCL) infused with nanosized synthetic smectic clay is a promising innovation in biomaterials for bone tissue engineering (BTE). The main challenge lies in achieving a uniform distribution of nanoceramics across low to high concentrations within the polymer matrix while preserving mechanical properties and biological performance essential for successful osseointegration.
Methods: This study utilized 3D printing to fabricate PCL scaffolds enriched with nanosized synthetic smectic clay (LAP) to evaluate its effects on structural, chemical, thermal, mechanical, and degradative properties, with a focus on in vitro biological performance and non-toxicity.
Process-based screening of porous materials for vacuum swing adsorption based on 1D classical density functional theory and PC-SAFT.
Mol Syst Des Eng
January 2025
Energy & Process Systems Engineering, Department of Mechanical and Process Engineering, ETH Zurich Zurich Switzerland
Adsorption-based processes are showing substantial potential for carbon capture. Due to the vast space of potential solid adsorbents and their influence on the process performance, the choice of the material is not trivial but requires systematic approaches. In particular, the material choice should be based on the performance of the resulting process.
View Article and Find Full Text PDFImine-Linked 3D Covalent Organic Framework Membrane Featuring Highly Charged Sub-1 nm Channels for Exceptional Lithium-Ion Sieving.
Adv Mater
January 2025
College of Energy, Key Laboratory of Core Technology of High Specific Energy Battery and Key Materials for Petroleum and Chemical Industry, Soochow University, Suzhou, 215006, China.
Coupling ion exclusion and interaction screening within sub-nanoconfinement channels in novel porous material membranes hold great potential to realize highly efficient ion sieving, particularly for high-performance lithium-ion extraction. Diverse kinds of advanced membranes have been previously reported to realize this goal but with moderate performance and complex operations gained. Herein, these issues are circumvented by preparing the consecutive and intact imine-linked three-dimensional covalent organic framework (i.
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