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Cytoreduction and Hyperthermic Intrathoracic Chemotherapy for Metastatic Pseudomyxoma Peritonei.
Ann Thorac Surg Short Rep
September 2024
Division of Thoracic Surgery, Mayo Clinic, Rochester, Minnesota.
Pleural extension of pseudomyxoma peritonei is rare, and treatment demands multidisciplinary care. Perioperative management during cytoreductive surgery and hyperthermic intrathoracic chemotherapy challenges anesthesiology and surgical teams in unique ways. Hemodynamic, arrhythmogenic, ventilatory, fluid balance, acid-base, and nephroprotection issues are important considerations.
View Article and Find Full Text PDFImplementation and evaluation of Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) for the treatment of patients with malignant pleural effusion: study protocol for the Danish phase-I PITAC-OPC5 study.
Pleura Peritoneum
December 2024
Odense PIPAC Center (OPC) and Odense Pancreas Center (OPAC), Odense University Hospital, Odense, Denmark.
Objectives: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) is a minimally invasive cancer-directed therapy for patients with malignant pleural effusion (MPE) and/or pleural metastasis (PLM). PITAC is based on Pressurized IntraPeritoneal Aerosol Chemotherapy, which has proven to be safe and feasible. Since 2012, 47 PITACs have been published, and prospective data on feasibility, safety and potential local response are lacking.
View Article and Find Full Text PDFPressurized IntraThoracic Aerosol Chemotherapy (PITAC) directed therapy of patients with malignant pleural effusion and pleural metastasis.
Pleura Peritoneum
December 2024
Odense PIPAC Center (OPC) and Odense Pancreas Center (OPAC), Odense University Hospital, Odense, Denmark.
Objectives: Pressurized IntraThoracic Aerosol Chemotherapy (PITAC) has been suggested as a new therapy for patients with malignant pleural effusion (MPE) and/or pleural metastasis (PLM). The patients have a poor prognosis with a median survival of 3 to 12 months. We present feasibility, patient safety, and cytological/histological response assessment in PITAC-treated patients with MPE and/or PLM.
View Article and Find Full Text PDFSliding hiatus hernia (intrathoracic sleeve migration) post-laparoscopic sleeve gastrectomy: A case series and review of literature.
J Minim Access Surg
January 2025
Department of General and Bariatric Surgery, King Hamad University Hospital, Busaiteen, Bahrain.
Article Synopsis
- * Diagnosis is confirmed through imaging techniques like gastrografin and CT scans, revealing issues such as GERD, hiatal hernias, and altered anatomy post-surgery.
- * Treatment often involves converting to Roux-en-Y bypass, but other options like laparoscopic hiatal hernia repair are also effective, with patients showing stability and no complications post-surgery.
A Case of Pancreatic Ductal Adenocarcinoma in an Elderly Adult With Heterotaxy Syndrome.
Cureus
July 2024
Gastroenterology, NewYork-Presbyterian (NYP) Brooklyn Methodist Hospital, Brooklyn, USA.
Article Synopsis
- Heterotaxy is a rare condition where organs are not properly positioned due to errors during embryonic development, often affecting the heart and other internal organs.
- A case study highlights an elderly patient with newly diagnosed pancreatic cancer who also had heterotaxy involving the stomach and spleen.
- The findings suggest that heterotaxy might increase the risk of gastrointestinal cancers and complicate surgical treatment, potentially leading to worse outcomes.
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