Background: Oxidised zirconium has the wear properties of ceramic with the breakage resistance of metal. This results in less wear and is of benefit to younger, higher demand patients. We report the short- to mid-term survival of 103 Profix zirconium total knee replacements performed in patients under 50years of age at time of surgery.
Methods: Data was collected prospectively and survival analysis undertaken with strict end points used. SF (Short Form) 12 and WOMAC (Western Ontario and McMaster University) scores were recorded at pre-operatively and at twelve months, one, three, five, seven and ten years.
Results: The average age at operation was 43.21years (range 20-50years) with a mean follow-up of 8.56years (range five to 15years). No patients died with one patient lost to follow-up after seven year review. The mean WOMAC score improved from 53 to 29, and the mean SF12 physical component improved from 29 to 36. The five year survivorship for implant related complications was 99.03% (95% CI 94.64-100.0) due to tibial component aseptic loosening at year one. Reoperation for any cause at five years including stiffness was 94.09% (95% CI 88.69-98.11). Forty-four patients were at least ten years post-operative at the time of analysis, with no aseptic loosening of either component giving 10year femoral component survival of 100% and all cause revision of 95.4%. The only zirconium femoral failure was at 12years.
Conclusions: Our data shows excellent mid-term survivorship of oxidised zirconium total knee replacements in younger, higher demand patients.
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http://dx.doi.org/10.1016/j.knee.2018.03.014 | DOI Listing |
J Bone Joint Surg Am
January 2025
Adult Reconstruction and Joint Replacement, Hospital for Special Surgery, New York, NY.
Background: Antiseptic solutions are commonly utilized during total joint arthroplasty (TJA) to prevent and treat periprosthetic joint infection (PJI). The purpose of this study was to investigate which antiseptic solution is most effective against methicillin-sensitive Staphylococcus aureus (MSSA) and Escherichia coli biofilms established in vitro on orthopaedic surfaces commonly utilized in total knee arthroplasty: cobalt-chromium (CC), oxidized zirconium (OxZr), and polymethylmethacrylate (PMMA).
Methods: MSSA and E.
Int J Biol Macromol
January 2025
Department of Chemistry, Amrita School of Physical Sciences, Coimbatore, Amrita Vishwa Vidyapeetham, 641112, India; Functional Materials Laboratory, Amrita School of Engineering, Coimbatore, Amrita Vishwa Vidyapeetham, 641112, India. Electronic address:
The effectiveness and safety of nanomaterials (NMs) are essential for their use in healthcare. This study focuses on creating NPs with multifunctional antibacterial and anticancer properties to combat bacterial infections and cancer disease more effectively than traditional antibiotics. This study investigates the synthesis of ZrO and chitosan (ch) coated zirconium oxide nanoparticles (chZrO NPs) using Bougainvillea glabra (B.
View Article and Find Full Text PDFJ Patient Rep Outcomes
January 2025
Division of Oral Surgery and Orthodontics, Department of Dental Medicine and Oral Health, Medical University of Graz, Graz, Austria.
Purpose: Zirconia dental implants show excellent biocompatibility and tissue integration, low affinity for plaque, and favorable biomechanical properties. However, these objective measures do not adequately replicate the patient's perception. This systematic review evaluated the evidence on patient-reported outcome (PROs) in zirconia dental implant treatment.
View Article and Find Full Text PDFMikrochim Acta
January 2025
Electroanalytical Chemistry Research Laboratory, Department of Analytical Chemistry, Faculty of Chemistry, University of Mazandaran, Babolsar, Iran.
A novel electrochemical aptasensor based on bimetallic zirconium and copper oxides embedded within mesoporous carbon (denoted as ZrOCuO@mC) was constructed to detect miRNA. The porous ZrOCuO@mC was created through the pyrolysis of bimetallic zirconium/copper-based metal-organic framework (ZrCu-MOF). The substantial surface area and high porosity of ZrOCuO@mC nanocomposite along with its robust affinity toward aptamer strands, facilitated the effective anchoring of aptamer strands on the ZrOCuO@mC-modified electrode surface.
View Article and Find Full Text PDFRSC Adv
January 2025
Institute of Intelligent Manufacturing Technology, Shenzhen Polytechnic University Shenzhen 518055 P. R. China
Supercapacitors (SCs) are gaining attention in energy storage due to their high-power density, rapid charge/discharge ability, and long life cycle. Improving these features relies on developing advanced electrode materials with better energy storage properties. This study explores UiO-66, a zirconium-based metal-organic framework (MOF), which offers advantages like a large surface area, tunable pore sizes, and stability.
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