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Diagnostic and prognostic potential of left atrial strain in cardiovascular disease: a narrative review.
J Echocardiogr
December 2024
Department of Cardiology, Lebanese American University Medical Center - Rizk Hospital, Beirut, Lebanon.
Left atrial strain (LAS) was recently introduced as a parameter that reflects on left atrial function. Consequently, changes in LAS can inform the development of cardiovascular diseases, hence providing a window for non-invasive and cost-effective testing of these diseases and their complications at early stages of development, potentially offering a segway towards preventive interventions. LAS has yet to be implemented into standard practice.
View Article and Find Full Text PDFComparative Efficacy of Endoscopic Versus Open Surgical Techniques in the Management of Gastric Outlet Obstruction: A Systematic Review.
Cureus
November 2024
Internal Medicine, Allama Iqbal Medical College, Lahore, PAK.
Gastric outlet obstruction (GOO) is a clinical condition that can arise from both benign and malignant causes, requiring effective management strategies to ensure optimal patient outcomes. Traditionally, open surgical techniques like gastrojejunostomy (GJ) have been the standard treatment, but recent advances in minimally invasive procedures, such as endoscopic ultrasound-guided gastroenterostomy (EUS-GE), offer alternative approaches with potentially reduced morbidity. This systematic review compared the efficacy, safety, and clinical outcomes of endoscopic versus open surgical techniques in managing GOO.
View Article and Find Full Text PDFNeuronal 'Ensemble' Recording and the Search for the Cell Assembly: A Personal History.
Hippocampus
January 2025
Department of Neurobiology and Behavior, University of California Irvine, Irvine, USA.
This contribution is part of the special issue on the Hippocampus focused on personal histories of advances in knowledge on the hippocampus and related structures. An account is offered of the author's role in the development of neural ensemble recording: stereo recording (stereotrodes, tetrodes) and the use of this approach to search for evidence of Hebb's "cell assemblies" and "phase sequences", the holy grail of the neuroscience of learning and memory.
View Article and Find Full Text PDFPremature coronary artery disease primary prevention - Searching for the Holy Grail.
Rev Port Cardiol
January 2025
Clínica Médica Jorge Alcaravela, Abrantes, Portugal; Serviço de Cardiologia, Centro Hospitalar Médio Tejo, Abrantes, Portugal; Abranclínica, Cardiologia, Portugal; Centro de Cardiologia de Intervenção, Hospital da Luz-Lisboa, Luz-Saúde, Portugal. Electronic address:
Evidence for a Role of Gut Microbiota and Probiotics in Aneurysmal Pathogenesis and Possible Therapeutics: A Systematic Review of the Literature.
High Blood Press Cardiovasc Prev
November 2024
Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon.
Introduction: Several studies investigated the implication of the gut microbiota (GM) in the formation and progression of aneurysms, suggesting a key role for GM metabolites in aneurysmal pathogenesis and prognosis.
Aim: This systematic review aims to collect key findings concerning the impact of gut bacterial compositions, GM-related metabolites, probiotics administration, and inflammatory markers in aneurysmal development and rupture.
Methods: A PubMed, Medline, Embase, and Web of Science database search was conducted in accordance with PRISMA guidelines for systematic reviews, targeting all studies assessing the GM's role in aneurysms till 2023.
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