Simple stacking of thin van der Waals 2D materials with different physical properties enables one to create heterojunctions (HJs) with novel functionalities and new potential applications. Here, a 2D material p-n HJ of GeSe/MoS is fabricated and its vertical and horizontal carrier transport and photoresponse properties are studied. Substantial rectification with a very high contrast (>10 ) through the potential barrier in the vertical-direction tunneling of HJs is observed. The negative differential transconductance with high peak-to-valley ratio (>10 ) due to the series resistance change of GeSe, MoS , and HJs at different gate voltages is observed. Moreover, strong and broad-band photoresponse via the photoconductive effect are also demonstrated. The explored multifunctional properties of the GeSe/MoS HJs are expected to be important for understanding the carrier transport and photoresponse of 2D-material HJs for achieving their use in various new applications in the electronics and optoelectronics fields.
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http://dx.doi.org/10.1002/smll.201704559 | DOI Listing |
J Cell Mol Med
December 2024
Department of Critical Care Medicine, the First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, P. R. China.
Sevoflurane's potential impact on cognitive function and neurodevelopment, especially in susceptible populations such as infants and the elderly, has raised widespread concern. This study focuses on how sevoflurane induces ferroptosis in astrocytes and identifies solute carrier family 7 member 11 (SLC7A11) as a mediator of ferroptosis, providing new insights into sevoflurane-related neurotoxic pathways. We analysed single-cell sequencing (scRNA-seq) data from sevoflurane-exposed mice and control mice, supplemented with bulk RNA-seq data, to assess gene expression alterations.
View Article and Find Full Text PDFSmall Methods
December 2024
School of Material Science and Engineering, National Institute of Technology Calicut, NIT Campus, Kozhikode, Kerala, 673601, India.
The work describes a novel sensing and transportation feasibility of the well-established antifungal drug Flucytosine (5-FC) using a 2D Silicon carbide (SiC) and Germanium-doped Silicon carbide (Ge@SiC) nanosheet via PBE level of Density functional theory. The computational study revealed that the drug molecules adhere to SiC and Ge@SiC sheets, maintaining their structural properties through physisorption on SiC and chemisorption on Ge@SiC. The charge transfer process associated with the adsorption is observed by Lowdin charge analysis and both the SiC and Ge@SiC sheets are identified as a feasible oxidation-based nanosensor for the drug.
View Article and Find Full Text PDFOphthalmic Genet
December 2024
Department of Ophthalmology, Bascom Palmer Eye Institute, Miami, Florida, USA.
Background: Pseudoxanthoma elasticum (PXE) is characterized by aberrant calcification of elastic tissues throughout the body causing varying degrees of skin, cardiac, and ocular disease. Although PXE is classically regarded as an autosomal recessive disease, recent reports have demonstrated a haploinsufficiency phenotype, in which carriers of monoallelic ATP-binding cassette transporter () gene mutations demonstrate mild manifestations of PXE. In this case report, we describe a patient with a monoallelic mutation and atypical angioid streaks.
View Article and Find Full Text PDFAngew Chem Int Ed Engl
December 2024
Shanghai Institute of Technology, School of Chemical and Environmental Engineering, CHINA.
Laminating a free-standing carbon electrode film onto perovskite film is a promising method for fabricating HTM (hole transport material)-free carbon electrode perovskite solar cells (c-PSCs), offering more flexibility by decoupling the processes of carbon electrode and perovskite layer formation. However, the power conversion efficiency (PCE) of laminated HTM-free c-PSCs (<16.5%) remains lower compared to c-PSCs with printed carbon pastes (>20%), primarily due to poor interfacial contact between the perovskite and carbon layers.
View Article and Find Full Text PDFAppl Radiat Isot
December 2024
Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, 730000, China; Advanced Energy Science and Technology Guangdong Laboratory, Huizhou, 516000, China; School of Nuclear Science and Technology, University of Chinese Academy of Sciences, Beijing, 100049, China.
Ac radionuclides have shown great potential for use as radiopharmaceuticals in cancer therapy by conjugation them with carrier molecules due to their strong cytotoxicity, suitable half-life, and ability to be used as Bi generators. The production of Ac via bombardment of Th targets with accelerated protons is currently the most widely used method in the world. In order to better quantify the achievable yields and radiopurity, this production process is simulated in this study.
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