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Holocord syringomyelia in 18 dogs.
Front Vet Sci
January 2025
Pride Veterinary Referrals, IVC Evidensia Group, Derby, United Kingdom.
Holocord syringomyelia (HSM) is characterized by a continuous spinal cord cavitation along its entire length and is currently poorly documented in dogs. This retrospective multicentric case series investigates the clinical and MRI findings in 18 dogs with HSM. The median age at presentation was 82 months (range 9-108 months) and French Bulldogs were overrepresented (50%).
View Article and Find Full Text PDFOn-chip non-contact mechanical cell stimulation - quantification of SKOV-3 alignment to suspended microstructures.
Heliyon
January 2025
Electrical and Computer Engineering, University of Canterbury, Christchurch, New Zealand.
Although the accumulation of random genetic mutations has been traditionally viewed as the main cause of cancer progression, altered mechanobiological profiles of the cells and microenvironment also play a major role as a mutation-independent element. To probe the latter, we have previously reported a microfluidic cell-culture platform with an integrated flexible actuator and its application for sequential cyclic compression of cancer cells. The platform is composed of a control microchannel in a top layer for introducing external pressure, and a polydimethylsiloxane (PDMS) membrane from which a monolithically-integrated actuator protrudes downwards into a cell-culture microchannel.
View Article and Find Full Text PDFIsolation, characterization and therapeutic efficacy of lytic bacteriophage ZK22 against Salmonella Typhimurium in mice.
BMC Microbiol
January 2025
Zhongkai University of Agriculture and Engineering, Guangzhou, 510225, Guangdong, China.
Background: Salmonella enterica serovar Typhimurium is one of the most common serovars of Salmonella associated with clinical cases. It not only leads to diarrhea and mortality raised in livestock and poultry farming, but also poses a risk to food safety.
Results: In this study, a lytic bacteriophage named ZK22 was isolated and identified from sewage.
Relationship between social anxiety and separation anxiety symptoms with insistence on sameness with the mediating role of sensory hypersensitivity.
BMC Psychol
January 2025
Faculty of psychology and educational sciences, University of Tabriz, Tabriz, Iran.
Background: Autism spectrum disorder (ASD) is characterized by impairments in social communication and interaction, restricted and repetitive patterns of behavior, and sensory processing abnormalities. These core features are often accompanied by comorbid anxiety disorders. However, the sequence and mechanisms of these associations warrant further investigation.
View Article and Find Full Text PDFSMILE-Derived Corneal Stromal Lenticule: Experimental Study as a Corneal Repair Material and Drug Carrier.
Cornea
January 2025
Chongqing Eye and Vision Care Hospital Aier Eye Hospital Group, Yu Zhong, Chongqing, China.
Purpose: A detailed study of the physicochemical properties of SMILE-derived lenticules and evaluation of their drug delivery after loading with silver nanoparticles (AgNPs).
Methods: The lenticules were decellularized and modified with crosslinking concentrations of 0.01 (0.
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