Enhanced JBrowse plugins for epigenomics data visualization.

BMC Bioinformatics

Department of Genetics, University of Georgia, Athens, GA, 30602, USA.

Published: April 2018

Background: New sequencing techniques require new visualization strategies, as is the case for epigenomics data such as DNA base modifications, small non-coding RNAs, and histone modifications.

Results: We present a set of plugins for the genome browser JBrowse that are targeted for epigenomics visualizations. Specifically, we have focused on visualizing DNA base modifications, small non-coding RNAs, stranded read coverage, and sequence motif density. Additionally, we present several plugins for improved user experience such as configurable, high-quality screenshots.

Conclusions: In visualizing epigenomics with traditional genomics data, we see these plugins improving scientific communication and leading to discoveries within the field of epigenomics.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921565PMC
http://dx.doi.org/10.1186/s12859-018-2160-zDOI Listing

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