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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5922202 | PMC |
| http://dx.doi.org/10.2105/AJPH.2017.304191 | DOI Listing |
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Background: Belzutifan, a first-in-class HIF-2α inhibitor, has shown antitumour activity as monotherapy and in combination with cabozantinib in patients with previously treated advanced kidney cancer. The phase 2 LITESPARK-003 study was designed to determine the antitumour activity and safety of belzutifan in combination with cabozantinib in patients with advanced clear-cell renal cell carcinoma that was previously untreated (cohort 1) or previously treated with immunotherapy (cohort 2). Here, we report results from cohort 1 of this clinical trial.
View Article and Find Full Text PDFA cross sectional analysis of residents by race/ethnicity and specialty from 2020-2023.
J Natl Med Assoc
December 2024
Department of Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, 200 1st St SW, Rochester, MN 55905, United States.
Background: Minorities are underrepresented in all areas of medical education relative to the United States general population, and minority physicians are more likely to practice in disadvantaged areas and in primary care settings. Many individual and structural factors contribute to this discrepancy. We aimed to demonstrate how resident race/ethnicity representation differs across the various resident specialties.
View Article and Find Full Text PDFShareable artificial intelligence to extract cancer outcomes from electronic health records for precision oncology research.
Nat Commun
November 2024
Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY, USA.
Databases that link molecular data to clinical outcomes can inform precision cancer research into novel prognostic and predictive biomarkers. However, outside of clinical trials, cancer outcomes are typically recorded only in text form within electronic health records (EHRs). Artificial intelligence (AI) models have been trained to extract outcomes from individual EHRs.
View Article and Find Full Text PDFAn Immediate but Fleeting Interest in MPH Programs After the Onset of COVID-19: An Interrupted Time-Series Analysis.
Public Health Rep
October 2024
Center for Anti-racism, Social Justice & Public Health, New York University School of Global Public Health, New York, NY, USA.
Objectives: The relationship between the onset of the COVID-19 pandemic and interest in master of public health (MPH) programs is unknown. We examined trends in MPH application rates for 31 MPH concentrations and specifically for the MPH concentration in epidemiology and differences by race and ethnicity before and after the onset of the COVID-19 pandemic.
Methods: We constructed a quasi-experimental design to examine trends in MPH application rates from academic years 2015-2016 through 2022-2023 by using Centralized Application Service for Schools and Programs of Public Health data.
Gender Differences in Self-Description: A Linguistic Analysis of Orthopedic Surgery Residency Application Personal Statements.
J Surg Educ
December 2024
The University of North Carolina, Department of Orthopaedics, Chapel Hill, North Carolina.
Objective: The purpose of this study is to assess differences in language characteristics in personal statements written by male and female applicants to an orthopedic surgery residency program.
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