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[Calcium metabolism in arterial hypertension. I. Myocardial hypertrophy and hormone-dependent increase in Ca2+ levels in the thrombocytes of patients with arterial hypertension]. | LitMetric
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[Calcium metabolism in arterial hypertension. I. Myocardial hypertrophy and hormone-dependent increase in Ca2+ levels in the thrombocytes of patients with arterial hypertension].

E B Tkhostov Sh E Atakhanov M Iu Men'shikov A P Iurenev A V Mazaev

Biull Vsesoiuznogo Kardiol Nauchn Tsentra AMN SSSR

Published: September 1988

Clonidine-treated patients with essential hypertension demonstrated reliable positive correlations between echocardiographically determined signs of myocardial hypertrophy (thickness of left ventricular posterior wall and interventricular septum, left ventricular myocardial mass) and hormone-dependent increase in thrombocyte calcium concentration induced by ADP and TAF. Antihypertensive therapy was more effective in patients with relatively weak cellular effect of Ca-increasing hormone response having no signs of myocardial hypertrophy.

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