AI Article Synopsis

  • - Intercellular adhesion molecule-1 (ICAM-1) is linked to atherosclerosis and inflammation, and this study explored its response to exhaustive submaximal exercise in healthy men.
  • - Thirteen healthy males participated in the study, undergoing exhaustive exercise while various health metrics like VO2max, BMI, and body fat percentage were measured.
  • - The results showed no significant change in serum ICAM-1 levels or correlations with the measured health metrics, suggesting that exhaustive submaximal exercise does not directly influence ICAM-1 or its relationship with inflammation in healthy individuals.

Article Abstract

Intercellular adhesion molecule-1 (ICAM-1) acts as the main factor in the occurrence of atherosclerosis and inflammatory diseases. This study aimed to investigate the response of ICAM-1to exhaustive submaximal exercise and its correlation with maximal oxygen consumption (VO2max), body mass index (BMI), waist-hip ratio (WHR), body fat percentage (BF %) and calories burned during exercise (CB) in healthy men. Thirteen healthy men (mean ± standard deviation: age 23 ± 3 years, weight 78 ± 4 kg, height 180 ± 4 cm) cooperated in this quasi-experimental study and performed a single bout of exhaustive submaximal exercise on a cycle ergometer. Blood samples were collected from the antecubital vein before and immediately after exercise. Data were analyzed using the paired sample t-test and Pearson's correlation coefficient (α=0.05). Exhaustive submaximal exercisehad no significant effect on serum sICAM-1. Also, there were no significant correlations between ICAM-1 induced by the exhaustive submaximal exercise and VO2max, BMI, WHR, BF % and CB. According to our findings, it cannot be ruled out that exhaustive submaximal exercise results in pathological and inflammatory conditions in healthy men. In Also, anthropometric and physiological parameters do not affect the response of ICAM-1 to exercise in healthy men.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909944PMC

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