Background/aim: The purpose of this study was to compare the clinical behavior of several grades of endometrioid carcinoma (EC) compared to high-grade serous carcinoma (HGSC), based on World Health Organization 2014 criteria.
Materials And Methods: Clinicopathological features were compared between all grades of EC and HGSC, and between HGSC and either grade 1/2 or grade 3 EC.
Results: Sixty-five patients with EC and 214 with HGSC were identified. Among patients with EC, 56 displayed 1/2 EC and nine had grade 3 EC. The progression-free (PFS) and overall (OS) survival of patients with grade 1/2 EC were better than of those of patients with HGSC; however, PFS and OS did not statistically differ between patients with grade 3 EC and those with HGSC. Grade 1/2 EC, but not grade 3, was a better prognostic factor compared with HGSC.
Conclusion: A grading system for EC would be beneficial for the accurate prognosis of ovarian cancer.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6000796 | PMC |
| http://dx.doi.org/10.21873/invivo.11281 | DOI Listing |
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