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| http://dx.doi.org/10.1016/j.bpj.2018.04.007 | DOI Listing |
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Similar Publications
Calsequestrin-mediated mechanism for cellular calcium transient alternans.
Biophys J
October 2008
Physics Department and Center for Interdisciplinary Research in Complex Systems, Northeastern University, Boston, Massachusetts, USA.
Intracellular calcium transient alternans (CTA) has a recognized role in arrhythmogenesis, but its origin is not yet fully understood. Recent models of CTA are based on a steep relationship between calcium release from the sarcoplasmic reticulum (SR) and its calcium load before release. This mechanism alone, however, does not explain recent observations of CTA without diastolic SR calcium content alternations.
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