Introduction: Classical deprivation instruments use a factor analytical approach relying on a smaller number of dimensions, factors or components. Multi-dimensional deprivation models attempt classification in fine detail-even down to street level.
Methods: Single-centre retrospective cohort study using routinely collected aggregated and anonymised data on emergency medical admissions (96,526 episodes in 50,731 patients; 2002-2016). We calculated admission/readmission rate incidences for the 74 small areas within the hospital catchment area. We compared a classical Small Area Health Research Unit (SAHRU) to the multi-dimensional POBAL Haase and Pratschke Deprivation Index for Small Areas (POBAL) deprivation instrument and their deprivation ranks for two Irish censuses (2006/ 2011).
Results: There was poor agreement between the instruments of the Deprivation Ranks by Quintile-with agreement in 46 and 42% of small areas for the respective 2006 and 2011 censuses. The classical model (SAHRU) suggested more areas with severe deprivation (Q5 66 and 55%) compared with POBAL (Q5 32 and 24%) from the respective censuses. SAHRU classical instrument had a higher prediction level incidence rate ratio (IRR) 1.48 (95% CI 1.47, 1.49)) compared with POBAL IRR 1.28 (95% CI 1.27, 1.28) and systematically lower estimates of hospital admission and readmission rate incidences. Earlier Census data modelled more powerfully, suggesting a long latency between social circumstances and the ultimate expression of the emergency medical admission.
Conclusion: Deprivation influences hospital incidence rates for emergency medical admissions and readmissions; instruments focusing at the very small area (individual or street level) have a utility but appear inferior in terms of representing the population risk of environmental/socio-economic factors which seem best approximated at a larger scale.
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http://dx.doi.org/10.1007/s11845-018-1815-0 | DOI Listing |
J Gastrointest Cancer
January 2025
Colorectal Research Center, Imam Khomeini Hospital complex, Tehran University of Medical Sciences, Keshavarz Blvd, Tehran, Iran.
Purpose: Carcinoembryonic antigen (CEA) is an important prognostic factor for rectal cancer. This study aims to introduce a novel cutoff point for CEA within the normal range to improve prognosis prediction and enhance patient stratification in rectal cancer patients.
Methods: A total of 316 patients with stages I to III rectal cancer who underwent surgical tumor resection were enrolled.
Langenbecks Arch Surg
January 2025
Department of Trauma Surgery, University Hospital Zurich, Rämistrasse 100, CH - 8091, Zurich, Switzerland.
Introduction: Blunt traumatic aortic injury (TAI) is a critical condition and a leading cause of mortality in trauma patients, often resulting from high-speed accidents. Thoracic endovascular aortic repair (TEVAR) has developed into the preferred therapeutic approach due to its minimally invasive nature and promising outcomes. This study evaluates the safety and efficacy of TEVAR for managing TAI over a 10-year period at a Level-1 trauma center.
View Article and Find Full Text PDFEur Radiol
January 2025
Department of Ultrasound, The First Medical Center, Chinese PLA General Hospital, No. 28 Fuxing Road, Haidian District, Beijing, 100853, China.
Objective: To compare the clinical outcomes of patients with unifocal paratracheal papillary thyroid microcarcinoma (PTMC) after thermal ablation (TA) vs. partial thyroidectomy (PT).
Materials And Methods: This retrospective multicenter study included 436 patients with unifocal, clinical N0 paratracheal PTMC who underwent TA (210 patients) or PT (236 patients) between June 2014 and December 2020.
Epigenetics
December 2025
Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.
Perceived discrimination, recognized as a chronic psychosocial stressor, has adverse consequences on health. DNA methylation (DNAm) may be a potential mechanism by which stressors get embedded into the human body at the molecular level and subsequently affect health outcomes. However, relatively little is known about the effects of perceived discrimination on DNAm.
View Article and Find Full Text PDFJpn J Clin Oncol
January 2025
Department of Thoracic Oncology, Kansai Medical University, 2-3-1 Shinmachi, Hirakata city, Osaka 573-1191, Japan.
Background: Pre-cancer onset of cachexia raises uncertainties regarding the optimal timing for early intervention in lung cancer patients. We aimed to examine changes in physical function, nutritional status, and cachexia incidence in patients with lung cancer from the initial visit to treatment initiation and determine the effect of these changes on lung cancer treatment.
Methods: This single-center retrospective cohort study enrolled patients suspected of having advanced lung cancer who visited Kansai Medical University Hospital between January and February 2023 and were definitely diagnosed with the disease.
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