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Hsp90 Interacts With Tm-2 and Is Essential for -Mediated Resistance to . | LitMetric

Hsp90 Interacts With Tm-2 and Is Essential for -Mediated Resistance to .

Front Plant Sci

MOE Key Laboratory of Bioinformatics, Center for Plant Biology, Tsinghua-Peking Joint Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing, China.

Published: April 2018

The tomato resistance gene encodes a coiled coil-nucleotide binding site-leucine rich repeat type resistance protein and confers effective immune response against tobamoviruses by detecting the presence of viral movement proteins (MPs). In this study, we show that the Heat shock protein 90-kD (Hsp90) interacts with Tm-2. Silencing of reduced -mediated resistance to (TMV) and the steady-state levels of Tm-2 protein. Further, Hsp90 associates with SGT1 in yeast and in plant cells. These results suggest that Hsp90-SGT1 complex takes part in -mediated TMV resistance by functioning as chaperone to regulate Tm-2 stability.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902563PMC
http://dx.doi.org/10.3389/fpls.2018.00411DOI Listing

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