Seroprevalences and Correlates of Hepatitis B and C Among Cameroonian Pregnant Women.

Clin Med Insights Reprod Health

Faculty of Health Sciences, School of Armies Health Services of Lomé, University of Lomé, Lomé, Togo.

Published: April 2018

Background And Rationale: Viral hepatitis B (VHB) and viral hepatitis C (VHC) are major public health issues in resource-poor countries where vertical transmission remains high.

Aim: To assess prevalences and correlates of VHB and VHC among women attending antenatal clinic.

Methods: A cross-sectional study at the Yaounde Central Hospital from January 1 to June 30, 2016. We included 360 pregnant women who were screened for hepatitis B virus surface antigen (HbsAg) and VHCAb by rapid diagnostic test (DiaSpot Diagnostics, USA) followed by confirmation of positive results by a reference laboratory. Odds ratios (95% confidence interval [CI]) were used to measure associations between variables. Statistical significance was set for -value <.05.

Results: Mean age was 27.9 ± 5.6 years. The prevalences of HbsAg and VHCAb were 9.4% (n = 34) and 1.7% (n = 6), respectively. Multiplicity of sex partners was significantly associated with HbsAg positivity (adjusted odds ratio [aOR]: 11.6; 95% CI: 5.1-26.7;  < .001) while none of the studied factors was associated with VHCAb.

Conclusion: The high prevalence of hepatitis B among pregnant women supports systematic screening and free vaccination of pregnant women and women of childbearing age.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5909852PMC
http://dx.doi.org/10.1177/1179558118770671DOI Listing

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