miR-33: A Metabolic Conundrum.

Trends Endocrinol Metab

Harvard Medical School and Massachusetts General Hospital Cancer Center, Building 149, 13th Street, Charlestown, MA, USA. Electronic address:

Published: October 2018

The miR-33 microRNAs (miRNAs) are crucial regulators of cholesterol/lipids, and may represent therapeutic targets for the treatment of atherosclerosis. A recent report by Price et al. showed that miR-33 knockout (KO) mice exhibit obesity, insulin resistance, and increased food intake, suggesting that metabolic regulation by miR-33 is more complex than was previously known.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151149PMC
http://dx.doi.org/10.1016/j.tem.2018.04.004DOI Listing

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