Presented herein are the outcomes of conservative treatment of patients suffering from post-thrombotic disease and chronic venous insufficiency of the lower extremities. Our open prospective randomized study included a total of eighty patients divided into two groups, each consisting of 40 people. All patients were subjected to standard comprehensive conservative treatment, with Group Two patients additionally prescribed Venarus. Efficacy of treatment for post-thrombotic disease was assessed with the use of the Villalta scale. The obtained findings demonstrated clinically significant improvement of the main clinical symptoms in Group Two patients, thus suggesting efficacy of the drug as soon as after a short period of administration. Treatment with Venarus in patients with distal forms of involvement of deep veins of the lower limbs was accompanied and followed by improvement of the tonicoelastic properties of the intact common femoral vein. Healing of small trophic ulcers was conditioned by efficacy of the drug at the level of the microcirculatory bed.
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Ther Adv Infect Dis
January 2025
Department of Biostatistics, College of Public Health, University of Kentucky, Lexington, KY, USA.
Background: Kentucky is one of seven states with high, sustained rural HIV transmission tied to injection drug use. Expanding access to pre-exposure prophylaxis (PrEP) has been endorsed as a key HIV prevention strategy; however, uptake among people who inject drugs (PWID) has been negligible in rural areas. Syringe services programs (SSPs) have been implemented throughout Kentucky's Appalachian region, providing an important opportunity to integrate PrEP services.
View Article and Find Full Text PDFFront Nutr
January 2025
School of Physical Education and Health, Nanchang Institute of Science & Technology, Nanchang, China.
Background: The increasing prevalence of psychological symptoms in adolescents has become an important problem faced by all countries in the world. The increased sugar-sweetened beverages (SSB) consumption and the decreased muscle strength had a serious negative impact on adolescent health. However, previous studies have mainly focused on adolescents in developed countries and fewer studies have been conducted in developing countries, especially in rural areas of western China.
View Article and Find Full Text PDFCurr Addict Rep
December 2024
APT Foundation, Inc., New Haven, CT, USA.
Purpose Of Review: We present current evidence on the associations among sleep, pain, and medications for opioid use disorder (MOUD) among individuals with opioid use disorder (OUD).
Recent Findings: We searched MEDLINE, Embase, PsycInfo, Web of Science, and Cochrane Library from inception until September 2023 for original research studies examining sleep, pain, and MOUD. We identified 19 manuscripts (14 were cross-sectional studies, four were prospective cohort studies, and one was a randomized controlled trial).
Indian J Orthop
February 2025
Department of Orthopaedics, JSS Medical College, Mysore, 570004 India.
Background: Rickets is a common metabolic bone disease in children, primarily caused by vitamin D deficiency. This study aimed to compare the efficacy of oral weekly vitamin D supplementation and injectable stoss therapy in treating nutritional rickets in Indian children.
Methods: This prospective, randomized, controlled trial was conducted over 18 months at a tertiary care center.
Orthop J Sports Med
January 2025
Clinica Ortopedica e Traumatologica II, Istituto Ortopedico Rizzoli, Bologna, Italy.
Background: In recent years, lateral extra-articular tenodesis (LET) has been shown to be promising in reducing the graft failure rate at short-term follow-up. However, there is a lack of studies investigating the incidence of complications and lateral osteoarthritis (OA) after this procedure, and only a few studies have reported long-term results after anterior cruciate ligament (ACL) reconstruction.
Purpose/hypothesis: This study aimed to compare the failure rate, clinical outcomes, and OA incidence of 3 different ACL reconstruction techniques: single-bundle quadrupled hamstring tendon (HT), bone-patellar tendon-bone (BPTB), and over-the-top HT plus LET (HT + LET).
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