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Gluteal Augmentation: A Historical Perspective on Aesthetic Practice.
Aesthet Surg J Open Forum
December 2024
Buttock augmentation has emerged as a significant focus in cosmetic surgery, driven by advancements in techniques and increasing patient interest in body contouring. The evolution of this field, from early pioneering methods to modern, diverse approaches, highlights the need to understand the specific characteristics of each technique and their implications for aesthetic outcomes. The author aims to provide a detailed review of 4 major buttock augmentation techniques: gluteal implants, Brazilian butt lift (BBL), intramuscular polymethylmethacrylate (PMMA), and deep subcutaneous hyaluronic acid fillers.
View Article and Find Full Text PDFPeripheral Nerve Stimulation for Chronic Neuropathic Pain: A Health Technology Assessment.
Ont Health Technol Assess Ser
January 2025
Background: Chronic neuropathic pain is a major health problem that adversely affects people's physical and mental well-being, as well as their quality of life. Percutaneous peripheral nerve stimulation (PNS) may offer a minimally invasive option earlier in the treatment continuum for adults with chronic neuropathic pain that is refractory to conventional medical management. We conducted a health technology assessment of PNS for adults with chronic neuropathic pain, which included an evaluation of effectiveness, safety, cost-effectiveness, the budget impact of publicly funding PNS, and patient preferences and values.
View Article and Find Full Text PDFSafety profile of EZH2 inhibitors for cancer: a systematic review and meta-analysis.
PeerJ
January 2025
Gastrointestinal Cancer Center, Chongqing University Cancer Hospital, Chongqing, China.
Objective: To evaluate the safety profiles of EZH2-targeted inhibitors in cancer treatment, focusing on treatment-related adverse events (TRAEs) across various clinical trials.
Methods: We conducted a systematic review and meta-analysis using data from clinical trials involving EZH2 inhibitors reported up to May 31, 2024. Databases searched included PubMed, Embase, CENTRAL (Cochrane Central Register of Controlled Trials), and ClinicalTrials.
Liquid biopsy for Renal Cell Carcinoma: A comprehensive review of techniques, applications, and future prospects.
Kidney Cancer
February 2024
University of California San Diego, San Diego, CA, USA.
Liquid biopsy techniques have developed rapidly in recent years and demonstrated success in cancer detection, disease characterization, and ongoing disease monitoring. These components, including circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), and cell-free DNA (cfDNA), offer minimally invasive diagnostic tools that provide valuable insights into the genomic landscape of tumors. Its applications have expanded to include various malignancies, including renal cell carcinoma (RCC).
View Article and Find Full Text PDFHidden blood loss and risk factors after percutaneous endoscopic transforaminal lumbar interbody fusion.
Front Surg
January 2025
Research Institute of Orthopedics, The Affiliated Jiangnan Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Purpose: In this study, we aimed to assess the occurrence of hidden blood loss (HBL) and its associated risk factors in patients with lumbar degenerative diseases who underwent percutaneous endoscopic transforaminal lumbar interbody fusion (Endo-TLIF).
Methods: Sex, age, height, weight, body mass index, and medical history including hypertension, diabetes, and osteoporosis were recorded. The duration of symptoms, preoperative lumbar subcutaneous fat tissue thickness (measured using midsagittal T2-weighted magnetic resonance imaging), lumbar disc degeneration grade, and other basic patient information were also documented.
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