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Factor XIa Inhibitor Reversal in Intracranial Hemorrhage: A Case Report.
Neurohospitalist
January 2025
Department of Neurology, Division of Neurocritical Care, University of North Carolina, Chapel Hill, NC, USA.
Background/objectives: There is currently no consensus regarding the optimal strategy for reversal of anticoagulation in life-threatening hemorrhage associated with factor XIa (FXIa) inhibitors.
Methods: For this clinical case report, informed consent was obtained from surrogate.
Results And Discussion: Here, we present the case of an 82-year-old female who sustained a large subdural hematoma after a fall.
Comparison of background characteristics and neuropathology findings between medico-legal autopsy cases with traumatic axonal injury, vascular axonal injury, or absence of axonal injury in β-amyloid precursor protein stain.
Int J Legal Med
January 2025
Department of Forensic Medicine, University of Helsinki, P.O. Box 21, Helsinki, FI-00014, Finland.
In forensic neuropathology, the β-amyloid precursor protein (β-APP) immunostain is used to diagnose axonal injury (AI). The two most common aetiologies are traumatic (TAI) and ischaemic (vascular; VAI). We aimed to identify background characteristics and neuropathology findings that are suggestive of TAI, VAI, or no AI in neuropathologically examined medico-legal autopsy cases.
View Article and Find Full Text PDFCentral nervous system vascular complications associated with the acute form of steroid-responsive meningitis-arteritis.
Vet J
January 2025
Departament de Medicina i Cirurgia Animals, Facultat de Veterinària, Universitat Autònoma de Barcelona, Bellaterra, Barcelona 08193, Spain; Fundació Hospital Clínic Veterinari, Facultat de Veterinària, Universitat Autònoma de Barcelona, Bellaterra, Barcelona 08193, Spain. Electronic address:
This retrospective study aims to describe the vascular events in the central nervous system (CNS) associated with the acute form of steroid-responsive meningitis-arteritis (SRMA), to compare the clinical features of dogs with and without such complications and to potentially identify predisposing factors for these events. Dogs with a presumptive diagnosis of SRMA visited between 2018 and 2023 with full medical records that underwent neurological examination, blood testing, cervical computed tomography or magnetic resonance imaging and cerebrospinal fluid (CSF) analysis were included. Thirty-three dogs were included and divided in two groups.
View Article and Find Full Text PDFREPRINTED FROM THE 2023 HYPERBARIC INDICATIONS MANUAL 15 Edition:Intracranial Abscess.
Undersea Hyperb Med
January 2025
The term "intracranial abscess" (ICA) includes cerebral abscess, subdural empyema, and epidural empyema, which share many diagnostic and therapeutic similarities and, frequently, very similar etiologies. Infection may occur and spread from a contiguous infection such as sinusitis, otitis, mastoiditis, or dental infection; hematogenous seeding; or cranial trauma. Brain abscess usually results from predisposing factors such as HIV infection, immunosuppressive drug treatment, surgery, adjacent infection (i.
View Article and Find Full Text PDFMiddle meningeal artery embolization for recurrent subdural hematoma in an extra-intracranial anastomosis patient on anticoagulant medication: A case report.
Sci Prog
January 2025
Department of Neurosurgery, Medical University Innsbruck, Innsbruck, Austria.
Symptomatic chronic subdural hematoma (cSDH) is amongst the most frequent neurological diseases with an upward trend due to an aging society and development in the field of anticoagulation therapies. Lately, subgaleal drainages and middle meningeal artery (MMA) embolization have been introduced to the standard armamentarium as treatment options for cSDH patients. Vascular anomalies, such as internal carotid artery (ICA) occlusion with spontaneous extra-intracranial anastomoses, usually lead to forfeiting embolization treatment from patients.
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