Background/aims: Several previous studies suggest that eradication of () leads to the disappearance of gastric hyperplastic polyps. However, little is known about the effect of status and eradication on the recurrence of gastric polyps after endoscopic removal. Here, we investigated the recurrence of gastric polyps according to the final status in patients who underwent endoscopic removal of gastric hyperplastic polyps.

Methods: Between January 2011 and December 2016, patients who underwent endoscopic removal of gastric hyperplastic polyps and were followed-up for more than two months were enrolled. The success of eradication was assessed by histology and rapid urease test or urea breath test, at least 4 weeks after the completion of eradication treatment. At follow-up, the recurrence of gastric polyp was evaluated via esophagogastroduodenoscopy.

Results: Seventy-nine patients were enrolled. During the mean follow-up period of 16.4 months, the recurrence rate of gastric polyp was 25.3%. Among those who received eradication therapy, the persistent group showed a higher recurrence of polyp than the eradicated group; but there was no statistical significance (42.9% vs. 21.7%, p=0.269). Regarding the final infection status, the recurrence rate of gastric polyps was significantly higher in the positive group than in the negative group (42.9% vs. 18.9%, p=0.031). In multivariate analysis, the final infection status was a significant risk factor for gastric polyp recurrence after endoscopic removal.

Conclusions: The final positive infection status is significantly associated with higher recurrence of gastric hyperplastic polyps after endoscopic removal.

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http://dx.doi.org/10.4166/kjg.2018.71.4.213DOI Listing

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