Protective effect of apple mangrove Sonneratia caseolaris extract in Edwardsiella tarda-infected African catfish, Clarias gariepinus.

Fish Shellfish Immunol

School of Fisheries and Aquaculture Sciences, Universiti Malaysia Terengganu, 21030 Kuala Terengganu, Terengganu, Malaysia; Institute of Tropical Aquaculture, Universiti Malaysia Terengganu, 21030 Kuala Terengganu, Terengganu, Malaysia. Electronic address:

Published: July 2018

AI Article Synopsis

  • Edwardsiellosis negatively affects African catfish aquaculture, prompting research on the protective benefits of apple mangrove extract against the infection.
  • The study found that higher doses of the Sonneratia caseolaris extract improved growth and survival rates in the fish, along with increased white blood cell counts indicating a stronger immune response.
  • Histopathological analysis showed tissue regeneration in the kidneys of treated fish, contrasting with damage seen in untreated fish, emphasizing the extract's protective properties against E. tarda infection.

Article Abstract

Outbreaks of edwardsiellosis have severe impact on the aquaculture production of African catfish Clarias gariepinus. In this study, feed supplemented with apple mangrove Sonneratia caseolaris extract was evaluated for its protective effect against Edwardsiella tarda infection in African catfish. Results showed an increase in growth performance and higher survival rate in the treatment groups in a dose dependent manner. Haematological analyses showed an increase in white blood cell count in the treatment groups. Histopathological analysis revealed degenerative changes and regeneration of liver tissue architecture in both the control and treatment groups. However, the presence of inflammatory cells was found exclusively in the kidney of T3 treatment group that was supplemented with the highest dose of extract at 3.17 mg/ml, which inferred the activation of immune response in the fish. Contrast to the deteriorative alteration observed in the kidney of the control group due to E. tarda infection, treatment group exhibited tissue regeneration and well-defined kidney tissue architecture at 3 dpi. Taken together, these results demonstrated that supplementation with the methanol extract of S. caseolaris possesses protective effect in African catfish against the infection of E. tarda.

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Source
http://dx.doi.org/10.1016/j.fsi.2018.04.033DOI Listing

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