Hemicrania continua (HC) is a rare primary headache disorder, characterized by persistent unilateral pain associated with cranial autonomic symptoms and prompt response to indomethacin. While migrainous features (including aura) have been recognized in cluster headache, there have been only single reports of HC with aura. Here, we report the case of a 53-year-old man with constant right-sided headache and superimposed exacerbations to severe pain lasting for several hours. Secondary etiologies were excluded, and a diagnosis of HC was established after prompt and complete response to treatment with indomethacin. During an episode of pain exacerbation, for the first time the patient experienced an episode of transient visual disturbances compatible with scintillating scotoma. We propose a potential link between HC and visual aura, which parallels similar observations in other trigeminal autonomic cephalalgias and more specifically confirms previous observational data on aura in HC, thus highlighting potentially shared pathophysiological mechanisms.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903150PMC
http://dx.doi.org/10.1159/000487881DOI Listing

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Article Synopsis
  • A case study reports a 54-year-old man with a history of episodic migraine who developed hemicrania continua (HC) and persistent visual aura lasting 15 months, with his aura symptoms only improving after treatment with divalproex sodium.
  • Visual aura, usually specific to migraine, has been linked to HC, but in this case, the aura continued despite successful headache treatment with indomethacin, indicating different underlying mechanisms.
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