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Chronic Endometritis and Endometriosis: Two Sides of the Same Coin?
Reprod Sci
January 2025
Department of Gynecology and Obstetrics, Cantonal Hospital of Schaffhausen, Geissbergstrasse 81, 8208, Schaffhausen, Switzerland.
Both chronic endometritis and endometriosis are common entities in infertile patients. The association and the co-existence of these two entities are poorly evaluated. The aim of this systematic review and meta-analysis was to examine the association between chronic endometritis and endometriosis and to find the prevalence of chronic endometritis in women with endometriosis.
View Article and Find Full Text PDFEndometrial scratching before euploid embryo transfer: a case-control study.
J Assist Reprod Genet
January 2025
Department of Obstetrics and Gynecology, Atrium Health Wake Forest Baptist, 1 Medical Center Blvd, Watlington Hall, Winston-Salem, NC, 27157, USA.
Purpose: To evaluate the effect of endometrial scratching on in vitro fertilization (IVF) success rates in women undergoing frozen embryo transfer with preimplantation genetic testing for aneuploidy (PGT-A).
Methods: Biopsy was performed at oocyte retrieval in cases and compared to those who did not undergo scratching (controls). Endpoints included pregnancy loss, total pregnancy, clinical pregnancy rate (CPR), ongoing pregnancy rate/live birth rate (OPR), and the incidence of chronic endometritis (CE).
Factors influencing endometrial receptivity in women with recurrent implantation failure.
BMC Womens Health
January 2025
OVIklinika Infertility Center, Połczyńska 31, Warsaw, 01-377, Poland.
Background: Embryo implantation involves two key elements: a good quality embryo and receptive endometrium. Endometrial receptivity abnormalities are known as one of the possible causes of recurrent implantation failure (RIF), especially when the embryo is euploid. This study was aimed to evaluate the impact of age and other clinical factors on endometrial receptivity in women with RIF.
View Article and Find Full Text PDFMid-infrared spectroscopy as a real-time diagnostic tool for chronic endometritis: A preliminary study.
Spectrochim Acta A Mol Biomol Spectrosc
December 2024
IVF Unit, Hillel Yaffe Medical Center, Hadera, Israel; Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 3109601, Israel.
Research Question: Can attenuated total reflection-Fourier transform infrared spectroscopy combined with machine learning techniques be used to develop a real-time diagnostic modality for chronic endometritis by analysing endometrial biopsies obtained during hysteroscopy?
Design: Women undergoing hysteroscopy for infertility assessment were enrolled in this prospective study from January 2020 to March 2021. Endometrial biopsies were evaluated using a spectrophotometer, and subsequently via histopathology, including immunohistochemical staining for the multiple myeloma oncogene-1 (MUM-1). Spectroscopy analyses of the positive and the negative chronic endometritis groups were compared across various cut-offs of MUM-1 positive cells per 10 high-power fields (HPF).
[Impact of gonadotropin-releasing hormone agonist on pregnancy outcomes in frozen-thawed embryo transfer cycles for patients with recurrent implantation failure combined with chronic endometritis].
Zhonghua Yi Xue Za Zhi
January 2025
Department of Human Reproductive Medicine, Beijing Obstetrics and Gynecology Hospital/Beijing Maternal and Child Health Care Hospital Affiliated to Capital Medical University, Beijing100026, China.
To explore the impact of gonadotropin-releasing hormone agonist (GnRH-a) on the pregnancy outcomes in frozen-thawed embryo transfer cycles for patients with recurrent implantation failure (RIF) complicated by chronic endometriti (CE). A total of 138 patients with RIF combined with CE who underwent in vitro fertilization/intracytoplamic sperm injection treatment-embryo transfer in the Department of Reproductive Medicine, Beijing Obstetrics and Gynecology Hospital, Capital Medical University from January 2020 to December 2023 were retrospectively included. According to the endometrial preparation protocol, they were divided into two groups: the pituitary downregulation group (=59) and the artificial cycle group (=79).
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