AI Article Synopsis
- The study investigates the ability of peptides from camel milk proteins to inhibit key digestive enzymes (DPP-IV, PPA, and PPL).
- Results showed significant inhibition of DPP-IV and PPL after enzyme hydrolysis, with some effect on PPA.
- Specific peptides were identified as the most effective inhibitors for each enzyme, showcasing the potential health benefits of camel milk proteins.
Article Abstract
In-vitro inhibitory properties of peptides released from camel milk proteins against dipeptidyl peptidase-IV (DPP-IV), porcine pancreatic α-amylase (PPA), and porcine pancreatic lipase (PPL) were studied. Results revealed that upon hydrolysis by different enzymes, camel milk proteins displayed dramatic increase in inhibition of DPP-IV and PPL, but slight improvement in PPA inhibition was noticed. Peptide sequencing revealed a total of 20 and 3 peptides for A9 and B9 hydrolysates respectively, obtained the score of 0.8 or more on peptide ranker and were categorized as potential DPP-IV inhibitory peptides. KDLWDDFKGL in A9 and MPSKPPLL in B9 were identified as most potent PPA inhibitory peptide. For PPL inhibition only 7 and 2 peptides qualified as PPL inhibitory peptides from hydrolysates A9 and B9, respectively. The present study report for the first time PPA and PPL inhibitory and only second for DPP-IV inhibitory potential of protein hydrolysates from camel milk.
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| http://dx.doi.org/10.1016/j.foodchem.2018.03.082 | DOI Listing |
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