We studied the excitation functions of residual radionuclides produced via proton and deuteron bombardment on natural iridium in the energy ranges of 30-15 MeV and 50-15 MeV, respectively. A conventional stacked-foil activation technique combined with HPGe γ-ray spectrometry was used to measure the excitation functions for Pt and Ir radionuclide production. Theoretical thick target yields were estimated to be 172 MBq/µA h and 192 MBq/µA h via the Ir(p,3n)Pt reaction at 29.6-17.5 MeV and the Ir(d,4n)Pt reaction at 40.3-23.8 MeV, respectively. The feasibility of Pt production from an iridium target was discussed, and compared with previously reported methods for the production of Pt.
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http://dx.doi.org/10.1016/j.apradiso.2018.03.021 | DOI Listing |
Front Neuroinform
January 2025
Department of Computer Science and Engineering, Institute of Technology, Nirma University, Gujarat, India.
Introduction: The prevalence of age-related brain issues has risen in developed countries because of changes in lifestyle. Alzheimer's disease leads to a rapid and irreversible decline in cognitive abilities by damaging memory cells.
Methods: A ResNet-18-based system is proposed, integrating Depth Convolution with a Squeeze and Excitation (SE) block to minimize tuning parameters.
Front Neural Circuits
January 2025
Department of Neurobiology, Hokkaido University Graduate School of Medicine, Sapporo, Japan.
A strong repetitive stimulus can occasionally enhance axonal excitability, leading to the generation of afterdischarge. This afterdischarge outlasts the stimulus period and originates either from the physiological spike initiation site, typically the axon initial segment, or from ectopic sites for spike generation. One of the possible mechanisms underlying the stimulus-induced ectopic afterdischarge is the local depolarization due to accumulated potassium ions surrounding the axonal membranes of the distal portion.
View Article and Find Full Text PDFHeliyon
January 2025
Institute of Biomedicine of Málaga (IBIMA), 29010, Málaga, Spain.
Background: Chronic kidney disease is a global problem characterized by a progressive decrease in kidney function with associated symptoms. A better understanding of these symptoms could lead to the development of personalized strategies.
Objective: This systematic review aims to describe the clusters of symptoms in kidney failure and categorize them according to their time of onset and how disabling they are for patients.
Chemistry
January 2025
Middle East Technical University: Orta Dogu Teknik Universitesi, Chemistry, Universiteler Mah., 06800, Cankaya, TURKEY.
This study introduces a new donor group capable of activating click-type [2+2] cycloaddition-retroelectrocyclizations, generally known for their limited scope. Target chromophores were synthesized using isocyanate-free urethane synthesis. The developed synthetic method allows for the tuning of the optical properties of the chromophores by modifying the donor groups, the acceptor units, and the side chains.
View Article and Find Full Text PDFNMR Biomed
March 2025
Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
The purpose of this study was to measure T and T relaxation times of NAD proton resonances in the downfield H MRS spectrum in human brain at 7 T in vivo and to assess the propagation of relaxation time uncertainty in NAD quantification. Downfield spectra from eight healthy volunteers were acquired at multiple echo times to measure T relaxation times, and saturation recovery data were acquired to measure T relaxation times. The downfield acquisition used a spectrally selective 90° sinc pulse for excitation centered at 9.
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