Nuclear import receptors are central players in transporting protein cargoes into the nucleus. Moving beyond this role, four newly published articles describe a function in regulating supramolecular assemblies by fine-tuning the phase separating properties of RNA-binding proteins, which has implications for a variety of devastating neurodegenerative disorders.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7611746 | PMC |
http://dx.doi.org/10.1016/j.cell.2018.04.002 | DOI Listing |
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