Purpose: Patients with cancer of the lower and middle rectum who are candidates for curative surgery often have negative opinions on definitive colostomy. The purpose of this study is to compare the quality of life (QoL) of patients who undergo standard treatment for rectal cancer with sphincter preservation or definitive colostomy.
Methods: A total of 125 patients with adenocarcinoma of the lower or middle rectum who underwent radical surgery with curative intent with a follow-up ≥ 1 year were recruited: 83 patients (group 1) were subjected to low anterior resection and low colorectal or coloanal anastomosis-thus preserving their sphincter-and 42 (group 2) were treated with abdominoperineal resection, followed by terminal definitive colostomy. QoL was assessed with the EORTC QLQ-C30 and QLQ-CR29 questionnaires.
Results: Health and global quality of life were similar between groups; however, patients who underwent definitive colostomy had higher scores on the emotional (p value = 0.016) and cognitive function scales (p value = 0.017). Patients with sphincter preservation presented with more symptoms that were related to stool frequency (p value < 0.001), intestinal constipation (p value = 0.005), fecal incontinence (p value = 0.001), buttock pain (p value = 0.023), and nausea and vomiting (p value = 0.036), whereas patients with permanent colostomy had higher scores for dysuria (p value = 0.033).
Conclusion: Although global QoL scores did not differ between groups, patients who underwent definitive colostomy had significantly better functional and symptom scale scores, reflecting greater function with fewer symptoms.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060835 | PMC |
| http://dx.doi.org/10.1007/s00384-018-3044-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Colouterine Fistula: A Rare Presentation of Severe Diverticular Disease.
Cureus
November 2024
General Surgery, Mon Health Medical Center, Morgantown, USA.
Colouterine fistula as a sequela of diverticulitis is an extremely rare complication due to the extraordinarily thick layer of myometrium of the uterus. Because of this, an aggressive clinical evaluation is required to rule out other potential causes of fistula formation such as malignancy. However, imaging and laboratory techniques may be inconclusive, and surgery with pathologic analysis may be required for a definitive diagnosis.
View Article and Find Full Text PDFA rare case of acute large bowel obstruction due to colonic bezoars associated with pica in a pediatric patient: A case report.
Int J Surg Case Rep
November 2024
Department of Pediatric Surgery, Kanti Children Hospital, Kathmandu, Nepal.
Introduction: Colonic bezoars are undigested or partially digested materials that accumulate in the form of a mass in the colon. There are occasional reports of constipation and intestinal obstruction due to geophagia or pica. Bezoars are due to pica, which is commonly associated with iron deficiency anemia and psychiatry disorders.
View Article and Find Full Text PDFAcute presentation of short‑segment Hirschsprung's disease treated with Soave's procedure in a 20‑year‑old male: A case report and mini‑review of the literature.
Med Int (Lond)
November 2024
Division of Pathology, Hospital Angeles Chihuahua, 31217 Chihuahua, Chih., Mexico.
Article Synopsis
- Hirschsprung's disease is a congenital condition where no ganglion cells are present in the colon, affecting its ability to move waste; it can often be misdiagnosed, even into adulthood.
- A case study of a 20-year-old male showed that after years of untreated chronic constipation, he faced an intestinal obstruction that led to emergency surgery and a diagnosis of Hirschsprung's disease.
- The treatment involved Soave-type surgery, which was successful, and the study suggests that adults with long-term constipation issues may need to be evaluated for this disease.
Delayed vs single-staged abdominal wall reconstruction in contaminated ventral hernia.
Hernia
November 2024
Center for Abdominal Core Health, Cleveland Clinic, 2049 E 100th St, Desk, A-100, Cleveland, OH, 44106, USA.
Article Synopsis
- Surgeons face a choice between single-stage or delayed repair for contaminated ventral hernias, and this study compares outcomes of both methods regarding wound complications, hernia recurrence, and quality of life.
- Data was analyzed from patients who had abdominal wall reconstruction (AWR) with synthetic mesh from January 2014 to August 2023, assessing outcomes for those who had delayed and single-staged repairs.
- Findings showed that both groups had similar rates of wound complications, reoperations, and hernia recurrence, suggesting that either repair method might be equally effective in this context.
Clinical Outcomes, Patterns of Failure, and Salvage Therapies of a Large Modern Cohort of Patients With Anal Squamous Cell Carcinoma Treated With Definitive-Intent Intensity-Modulated Radiation Therapy.
Int J Radiat Oncol Biol Phys
November 2024
Department of Radiation Oncology, Colorectal and Anal Cancer Service, Memorial Sloan Kettering Cancer Center, New York, New York; Department of Medicine, Early Drug Development Service, Memorial Sloan Kettering Cancer Center, New York, New York. Electronic address:
Purpose: Patterns of failure and salvage therapy options for patients with anal squamous cell carcinoma (ASCC) who recur after definitive-intent intensity-modulated radiation therapy (IMRT) with concurrent chemotherapy are not well described.
Methods And Materials: We identified consecutive patients with ASCC treated with definitive-intent IMRT between July 2005 and December 2019. Relevant patient and tumor parameters, disease outcomes (locoregional failure [LRF], distant failure, progression-free survival, colostomy-free survival, and overall survival [OS]), patterns of failure, and salvage therapies were collected.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!