Rituximab (RTX) has become a standard therapy for certain B cell malignancies and autoimmune diseases. We report 2 RTX-treated patients who developed severe tick-borne encephalitis virus (TBEV) infection. The inability to generate new antibody responses renders RTX-treated patients susceptible to TBEV, impedes laboratory diagnosis, and necessitates preventive vaccination in endemic areas.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5903409 | PMC |
http://dx.doi.org/10.1093/ofid/ofx204 | DOI Listing |
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