Diterpenoids are the focus of natural product drug discovery because of their great structural diversity and pronounced biological activities. Steud is a Chinese traditional medicinal herb for curing edema, ascites, and cancer. This plant contains rich diterpenoids. Based on the carbon skeleton and substituents, it can be classified into thirteen subtypes: -abietane, daphnane, tigliane, ingenane, -atisane, -rosane, -kaurene, -kaurane, secotigliane, lathyrane, ent-pimarene, isopimarene and dimeric. In this paper, we reviewed the chemical structures and biological activities of 90 diterpenoids isolated from this medicinal herb. We hope that this work can serve as a reference for further research of these diterpenoids and lay the foundation for drug discovery.
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| http://dx.doi.org/10.3390/molecules23040935 | DOI Listing |
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