AI Article Synopsis
- The study aimed to establish reference levels for specific IgG antibodies in a healthy adult Omani population, as high levels can indicate severe health conditions.
- Conducted at Sultan Qaboos University Hospital, the research tested 125 healthy blood donors, initially finding non-normal data which was later transformed for analysis.
- The final reference range for specific IgG levels was determined to be 2.0-68.7 mg/L, aligning closely with findings from other populations.
Article Abstract
Objectives: The presence of abnormally high levels of -specific immunoglobulin (Ig) G antibodies can serve as a diagnostic criterion for severe conditions like allergic bronchopulmonary and chronic pulmonary aspergillosis. This study aimed to determine a reference range of -specific IgG levels within a healthy adult Omani population.
Methods: This study took place during November 2015 at the Sultan Qaboos University Hospital, Muscat, Oman. The of 125 healthy Omani blood donors were tested for specific IgG levels using an automated fluorescence enzyme immunoassay.
Results: Initially, the data were not normally distributed; however, log transformation and the exclusion of four outliers resulted in an acceptable Gaussian distribution. The reference range was 2.0-68.7 mg/L at the 2.5 and 97.5 percentiles, respectively, with 90% confidence intervals of 2.0-3.0 mg/L and 48.0-76.0 mg/L, respectively.
Conclusion: The specific IgG reference range within a healthy adult Omani population was comparable to those reported in other populations.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5892812 | PMC |
| http://dx.doi.org/10.18295/squmj.2018.18.01.007 | DOI Listing |
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